Enhancement of plant proteinase inhibitors for the protection of crop plants against insect attack
Enhancement of plant proteinase inhibitors for the protection of crop plants against insect attack
批准号:
LP0560794
负责人:
Prof David Craik
金额:
$17.48万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2005
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2005-06-21 至 2008-06-20
中文摘要
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英文摘要
The aim of this project is to characterise the interactions between various known plant proteinase inhibitors and the major digestive enzymes of insects by structural and dynamic studies and to utilise mutational studies to design new inhibitors that more effectively bind to target proteinases. The outcomes will be the knowledge to design specific inhibitors to give optimal inhibition of specific insect proteinases. This knowledge will lead to novel approaches to protect economically important crops, such as cotton, from insect pests in Australia - potentially saving tens of millions of dollars per annum in chemical pesticide use and enhancing crop production in Australia and internationally.
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