Discovery of novel circular proteins in bacteria, plants and animals: applications in drug design and crop protection
Discovery of novel circular proteins in bacteria, plants and animals: applications in drug design and crop protection
批准号:
DP0449500
负责人:
Prof David Craik
金额:
$121.64万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-07-31 至 2009-07-30
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The overall goal is to use innovative methods in chemistry, biochemistry and molecular biology to determine the structures and functions of several families of circular proteins that have exciting pharmaceutical and agricultural applications. These molecules differ from conventional proteins in that they have no ends: their termini are seamlessly joined, thereby making them exceptionally stable and resistant to enzyme digestion. The big question is ?How and why does Nature produce circular proteins?" Increasing our knowledge of why circular proteins have evolved will facilitate their applications in drug design and in the development of novel insecticides.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A peptide platform to fight pests threatening global food security
-
批准号:DP230100590
-
项目类别:Discovery Projects
-
资助金额:$45.75万
-
财政年份:2023
-
负责人:Prof David Craik
-
依托单位:
ARC Centre of Excellence for Innovations in Peptide and Protein Science
-
批准号:CE200100012
-
项目类别:ARC Centres of Excellence
-
资助金额:$2450.12万
-
财政年份:2021
-
负责人:Prof David Craik
-
依托单位:
Eco-friendly pesticides for crop protection
-
批准号:LP190100958
-
项目类别:Linkage Projects
-
资助金额:$32.55万
-
财政年份:2021
-
负责人:Prof David Craik
-
依托单位:
Plant cyclotides as novel sustainable tools for crop protection
-
批准号:LP200100064
-
项目类别:Linkage Projects
-
资助金额:$29.04万
-
财政年份:2021
-
负责人:Prof David Craik
-
依托单位:
A Nuclear Magnetic Resonance Facility for Modern Molecular Analysis
-
批准号:LE160100218
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$56.01万
-
财政年份:2016
-
负责人:Prof David Craik
-
依托单位:
Development of peptide-based scaffolds for intracellular cancer targets
-
批准号:nhmrc : 1084965
-
项目类别:Project Grants
-
资助金额:$98.68万
-
财政年份:2015
-
负责人:Prof David Craik
-
依托单位:
The chemistry and biology of circular proteins
-
批准号:DP150100443
-
项目类别:Discovery Projects
-
资助金额:$46.13万
-
财政年份:2015
-
负责人:Prof David Craik
-
依托单位:
Taking Australia from the farm to the pharm
-
批准号:FL150100146
-
项目类别:Australian Laureate Fellowships
-
资助金额:$210.26万
-
财政年份:2015
-
负责人:Prof David Craik
-
依托单位:
Development of eco-friendly alternatives for crop pest management
-
批准号:LP130100550
-
项目类别:Linkage Projects
-
资助金额:$33.4万
-
财政年份:2013
-
负责人:Prof David Craik
-
依托单位:
Research Fellowship - Grant ID:1026501
-
批准号:nhmrc : 1026501
-
项目类别:Research Fellowships
-
资助金额:$55.73万
-
财政年份:2012
-
负责人:Prof David Craik
-
依托单位:
Cyclic peptide based angiogenic inhibitors.
-
批准号:nhmrc : 1028509
-
项目类别:Project Grants
-
资助金额:$25.09万
-
财政年份:2012
-
负责人:Prof David Craik
-
依托单位:
Innovations in peptide-based drug design
-
批准号:LP110200213
-
项目类别:Linkage Projects
-
资助金额:$175.22万
-
财政年份:2011
-
负责人:Prof David Craik
-
依托单位:
Development of a scorpion toxin for tumour imaging
-
批准号:nhmrc : 1010552
-
项目类别:NHMRC Project Grants
-
资助金额:$35.31万
-
财政年份:2011
-
负责人:Prof David Craik
-
依托单位:
Discovery and applications of circular proteins
-
批准号:DP0984390
-
项目类别:Discovery Projects
-
资助金额:$62.74万
-
财政年份:2009
-
负责人:Prof David Craik
-
依托单位:
Uncoupled Research Fellowship
-
批准号:nhmrc : 569603
-
项目类别:NHMRC Research Fellowships
-
资助金额:$27.65万
-
财政年份:2009
-
负责人:Prof David Craik
-
依托单位:
Development of Novel antibacterial compounds from subtilosin A
-
批准号:nhmrc : 519734
-
项目类别:NHMRC Project Grants
-
资助金额:$32.72万
-
财政年份:2008
-
负责人:Prof David Craik
-
依托单位:
Bioengineering of Cyclotides with Angiogenic Properties
-
批准号:nhmrc : 401600
-
项目类别:NHMRC Project Grants
-
资助金额:$32.56万
-
财政年份:2006
-
负责人:Prof David Craik
-
依托单位:
New leads for Anti-Cancer Drug Development
-
批准号:nhmrc : 351590
-
项目类别:NHMRC Project Grants
-
资助金额:$21.75万
-
财政年份:2005
-
负责人:Prof David Craik
-
依托单位:
Enhancement of plant proteinase inhibitors for the protection of crop plants against insect attack
-
批准号:LP0560794
-
项目类别:Linkage Projects
-
资助金额:$17.48万
-
财政年份:2005
-
负责人:Prof David Craik
-
依托单位:
Applying the CCK framework to angiogenic-based therapeutics
-
批准号:LP0347380
-
项目类别:Linkage Projects
-
资助金额:$20.94万
-
财政年份:2003
-
负责人:Prof David Craik
-
依托单位:
国内基金
海外基金
登录
查看更多内容
Novel-miR-1134调控LHCGR的表达介导拟
穴青蟹卵巢发育的机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2025
-
负责人:崔文晓
-
依托单位:
novel-miR75靶向OPR2,CA2和STK基因调控人参真菌胁迫响应的分子机制研究
-
批准号:82304677
-
项目类别:青年科学基金项目
-
资助金额:30.00万元
-
批准年份:2023
-
负责人:边兴博
-
依托单位:
海南广藿香Novel17-GSO1响应p-HBA调控连作障碍的分子机制
-
批准号:82304658
-
项目类别:青年科学基金项目
-
资助金额:30万元
-
批准年份:2023
-
负责人:刘亚
-
依托单位:
白术多糖通过novel-mir2双靶向TRADD/MLKL缓解免疫抑制雏鹅的胸腺程序性坏死
-
批准号:32102747
-
项目类别:青年科学基金项目(C类)
-
资助金额:30.0万元
-
批准年份:2021
-
负责人:李婉雁
-
依托单位:
novel_circ_001042/miR-298-5p/Capn1轴调节线粒体能量代谢在先天性肛门直肠畸形发生中的作用机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:55万元
-
批准年份:2021
-
负责人:唐晓冰
-
依托单位:
novel-miR-59靶向HMGAs介导儿童早衰症细胞衰老的作用及机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:58万元
-
批准年份:2021
-
负责人:张瑜
-
依托单位:
novel_circ_008138/rno-miR-374-3p/SFRP4调控Wnt信号通路参与先天性肛门直肠畸形发生的分子机制研究
-
批准号:82070530
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2020
-
负责人:白玉作
-
依托单位:
miRNA-novel-272通过靶向半乳糖凝集素3调控牙鲆肠道上皮细胞炎症反应的机制研究
-
批准号:32002421
-
项目类别:青年科学基金项目
-
资助金额:24.0万元
-
批准年份:2020
-
负责人:修云吉
-
依托单位:
m6A修饰介导的lncRNA WEE2-AS1转录后novel-pri-miRNA剪切机制在胶质瘤恶性进展中的作用研究
-
批准号:82072775
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2020
-
负责人:薛皓
-
依托单位:
miRNA/novel_167靶向抑制Dmrt1的表达在红鳍东方鲀性别分化过程中的功能研究
-
批准号:31902347
-
项目类别:青年科学基金项目
-
资助金额:25.0万元
-
批准年份:2019
-
负责人:闫红伟
-
依托单位: