Development of a scorpion toxin for tumour imaging

用于肿瘤成像的蝎子毒素的开发

• 批准号: nhmrc : 1010552
• 负责人: Prof David Craik
• 金额: $ 35.31万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-scorpion-toxin-tumour-imaging/109503
• 关键词: Development; scorpion; toxin; tumour; imaging

The aim of this project is to develop a tool for visualising tumours during surgery. Surgical removal of tumours remains the foundation of cancer treatment, but the ability to distinguish the margin between cancerous and healthy cells is imprecise. We will explore the potential of a scorpion toxin that selectively targets cancer cells, as a tumour imaging agent. This project has the potential to dramatically enhance patient survival as a result of improving treatments for cancer.

该项目的目的是开发一种在手术过程中可视化肿瘤的工具。手术切除肿瘤仍然是癌症治疗的基础，但区分癌细胞和健康细胞的能力是不精确的。我们将探索一种选择性靶向癌细胞的蝎子毒素作为肿瘤显像剂的潜力。由于改善了癌症治疗，该项目有可能大大提高患者的生存率。