Analysis for genes specifically expressed in primate neocotical areas

灵长类新皮质区特异表达基因的分析

• 批准号: 17024055
• 负责人: YAMAMORI Tetsuo
• 金额: $ 85.5万
• 依托单位: National Institute for Basic Biology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17024055/
• 关键词: 大脳皮質; 領野; 遺伝子発現; 連合野; 視覚野; PNMA5; RBP; occl; セロトニン受容体; 大脳皮質領野; 活動依存性; 遺伝子; occ1; マカカ; c-Fos; 視聴覚; 脳特異的転写因子; アンチセンスRNA; 行動装置

We have identified the genes that are markedly expressed in primate neocortical areas by a large scale analysis and found that these genes can be classified into two groups: The primary visual area specific and association area specific genes. The two areas are highly developed in the primate neocortex and thus these genes may play certain important roles in the specification of the primate areas. We have also identified roles of 5HT1B and 5HT2A serotonin receptors.

我们通过大规模的基因分析，发现在灵长类动物新皮层区有显著表达的基因，并将其分为两类：初级视区特异性基因和联合区特异性基因。这两个区域在灵长类动物的新皮层中高度发达，因此这些基因可能在灵长类动物区域的特化中发挥一定的重要作用。我们还确定了5HT1B和5HT2A血清素受体的作用。

项目成果

7-12 Hz cortical oscillations : behavioral contex and dynamic s of prefrontal neuronal ensembles.

7-12 Hz 皮质振荡：前额神经元群的行为背景和动态。

• 发表时间: 2005
• 期刊: Neuroscience 134
• 作者: Sakata S;Yamamori T;Sakurai Y.;Takahata T.他;Sakata S.他
• 通讯作者: Sakata S.他

Analysis of Area-Specific Expression Patterns of RORbeta, ER81 and Nurr1 mRNAs in Rat Neocortex by Double In Situ Hybridization and Cortical Box Method

• DOI: 10.1371/journal.pone.0003266
• 发表时间: 2008-09-25
• 期刊: PLOS ONE
• 影响因子: 3.7
• 作者: Hirokawa, Junya;Watakabe, Akiya;Yamamori, Tetsuo
• 通讯作者: Yamamori, Tetsuo

Retinol-binding protein gene is highly expressed in higher-order association areas of the primate neocortex

• DOI: 10.1093/cercor/bhh112
• 发表时间: 2005-01-01
• 期刊: CEREBRAL CORTEX
• 影响因子: 3.7
• 作者: Komatsu, Y;Watakabe, A;Yamamori, T
• 通讯作者: Yamamori, T

Topological relationships between brain and social networks.

大脑和社交网络之间的拓扑关系。

• 发表时间: 2007
• 期刊: Neural Netw. 20(1)
• 作者: Sakata S;Yamamori T.
• 通讯作者: Yamamori T.

Activity-dependent expression of occ1 in excitatory neurons is a characteristic feature of the primate visual cortex.

兴奋性神经元中 occ1 的活动依赖性表达是灵长类视觉皮层的一个特征。

• 发表时间: 2006
• 期刊: Cereb Cortex. 16(7)
• 作者: Takahata T;Komatsu Y;Watakabe A;Hashikawa T;Tochitani S;Yamamori T.
• 通讯作者: Yamamori T.