600 MHz NMR spectrometer console

600 MHz 核磁共振波谱仪控制台

• 批准号: 508097909
• 金额: --
• 依托单位: Philipps-Universität Marburg
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2022
• 资助国家: 德国
• 起止时间: 2021-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/508097909?language=en
• 关键词: 600; MHz; NMR; spectrometer; console

NMR spectroscopy is the most important method for the analysis of molecular structures in the working groups of organic and inorganic chemistry at the Department of Chemistry. The analytical requirements range from structural analysis of CH scaffolds to the identification of heteronuclei to the characterization of intermolecular interactions or relaxation properties. The strongly experimentally oriented education brings students into contact with NMR spectroscopy at an early stage. As researchers, they have access to four 250-300 MHz routine spectrometers, two 500 MHz and one 600 MHz spectrometer at the department. The 600 MHz spectrometer is at the forefront of spectroscopic structure elucidation in Central Analytics NMR spectroscopy. While the 600 MHz spectrometer has the highest resolution of any existing instrument, the aging electronics (no investment has been made in the machine since its installation in 2005) are no longer up to the task of elucidating complex scientific questions. With the renewal of the 600 MHz NMR spectrometer console, new ranges of sensitivity can be opened up and new measurement techniques can be used that could not be used before. Technical developments in the field of hetero-nuclei allow the measurement of completely new correlation spectra. This concerns in particular the 19F correlations, a nucleus that is at the center of the molecular syntheses of several research groups. The technology is based on a transceive principle, i.e. each NMR channel has transmit and receive functions. Thus, each channel is its own independent spectrometer with complete RF generation, transmission and reception infrastructure. This architecture provides maximum flexibility in terms of instrument configuration and multi-channel operation. Multi-receive experiments can also be implemented, allowing simultaneous measurement on multiple frequency channels for more efficient use of measurement time.

NMR光谱是化学系有机和无机化学工作组分析分子结构的最重要方法。分析要求的范围从CH支架的结构分析到异核的鉴定，再到分子间相互作用或弛豫特性的表征。强烈的实验导向教育使学生在早期阶段接触NMR光谱学。作为研究人员，他们可以使用该部门的四台250-300 MHz常规光谱仪，两台500 MHz和一台600 MHz光谱仪。600 MHz光谱仪在Central Analytics NMR光谱学中处于光谱结构解析的最前沿。虽然600 MHz光谱仪具有现有仪器中最高的分辨率，但老化的电子设备（自2005年安装以来没有对机器进行过投资）不再能够完成阐明复杂科学问题的任务。随着600 MHz NMR光谱仪控制台的更新，可以开辟新的灵敏度范围，并可以使用以前无法使用的新测量技术。异质核领域的技术发展允许测量全新的相关谱。这特别涉及19 F相关性，这是几个研究小组分子合成的核心。该技术是基于一个双向原理，即每个NMR通道具有发送和接收功能。因此，每个通道都是独立的光谱仪，具有完整的RF生成，传输和接收基础设施。该架构在仪器配置和多通道操作方面提供了最大的灵活性。还可以实现多接收实验，允许在多个频率信道上同时测量，以更有效地利用测量时间。