Nanoparticle fluorescent labels as a platform for high throughput data gathering

纳米颗粒荧光标记作为高通量数据收集的平台

• 批准号: DP0451755
• 负责人: Prof Ewa Goldys
• 金额: $ 21.94万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-01-01 至 2007-12-21
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0451755
• 关键词: Nanoparticle; fluorescent; labels; platform; throughput

Recent developments in genomics require gathering of vast amounts of information in a rapid and cost-effective fashion. To this aim we will develop a new fluorescent labelling technology with adequate throughput and high level of multiplexing. We will exploit recent advances in nanoparticle science combined with our own discoveries concerning rare earth ions as fluorescence activators. Our approach promises a combination of great technological simplicity, low fabrication costs, cutting edge performance and gives an additional time-resolved modality. Our fluorescent labels will be field-tested to search for yet unknown microorganisms.

基因组学的最新发展要求以快速和具有成本效益的方式收集大量信息。为此，我们将开发一种新的荧光标记技术，具有足够的吞吐量和高水平的多重。我们将利用纳米粒子科学的最新进展，结合我们自己的发现，稀土离子作为荧光激活剂。我们的方法承诺结合了极大的技术简单性，低制造成本，尖端性能，并提供了一个额外的时间分辨模式。我们的荧光标记将进行实地测试，以寻找未知的微生物。