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The colour of cellular aging: a deep probe of cellular processes

The colour of cellular aging: a deep probe of cellular processes
细胞衰老的颜色:细胞过程的深入探索
批准号:
DP210102960
负责人:
Prof Ewa Goldys
金额:
$35.21万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2023-12-31

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中文摘要
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英文摘要
Understanding why we age and whether aging is preventable are profound research challenges, which must be first tackled at a cellular level. Building on our advances in non-invasive colour monitoring of cell function, this project aims to uncover intimate links between cellular processes and aging in cells that must survive for many decades such as oocytes and neurons. We will explore the tantalising possibility to rejuvenate such aged cells by interfering with molecular master switches of aging. A unique machine learning approach will be applied for finding the most effective interventions. The results will have broad impact beyond the science of aging, in the areas of female fertility, neurodegeneration and immunity.
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