On-site environmental DNA sensing with user-friendly test strips

使用用户友好的测试条进行现场环境 DNA 传感

• 批准号: DP240103024
• 负责人: Prof Ewa Goldys
• 金额: $ 41.67万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP240103024
• 关键词: site; environmental; DNA; sensing; user

Organisms shed their genes into the environment. This project aims to develop world-first field-portable biosensors for this environmental DNA. Based on a novel sensing principle, they will offer performance comparable with current laboratory-based techniques. They will be rapid (< 1 h), cost -effective (< $ 1 per strip) and robust. Project outcomes will include tube-based tests able to detect 1 DNA copy / microlitre and ultralight paper test strips, both with naked-eye readout. Applications of these sensors in water testing will be developed with an Australian industry partner Biopoint. Benefits will include strengthened protection against invasive pests and the spread of antimicrobial resistance without lab testing and sample logistics.

生物体将它们的基因释放到环境中。该项目旨在为这种环境DNA开发世界上第一个现场便携式生物传感器。基于一种新的传感原理，它们将提供与目前基于实验室的技术相当的性能。它们将是快速的（< 1小时）、具有成本效益的（每条<1美元）和稳健的。项目成果将包括能够检测1个DNA拷贝/微升的试管测试和超轻型试纸条，两者都具有裸眼读数。这些传感器在水测试中的应用将与澳大利亚行业合作伙伴Biopoint一起开发。好处将包括加强对入侵害虫的保护，以及在没有实验室测试和样本物流的情况下传播抗菌素耐药性。