Amplifying light emission with metal-fluorophore nanostructures for ultrasensitive biosensing

利用金属荧光团纳米结构放大光发射，实现超灵敏生物传感

• 批准号: DP0880876
• 负责人: Prof Ewa Goldys
• 金额: $ 25.54万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-08-27 至 2011-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0880876
• 关键词: Amplifying; light; emission; metal; fluorophore

This proposal focuses on translating nanotechnology to ultrasensitive molecular monitoring for biomedicine. We will apply a new tool, amplified fluorophores to proteomics where they will provide an improved method for early detection and understanding of diseases through molecular fingerprints. The project will also generate an ultra-sensitive, rapid technology that can be used for personalized point-of-care diagnostics. The applications can include the detection of disease markers, pathogens or the determination of protein content in a clinical sample. These technologies will be applicable across a spectrum or of diseases all of which will benefit the broader community.

该提案的重点是将纳米技术转化为生物医学的超灵敏分子监测。我们将应用一种新的工具，放大的荧光团蛋白质组学，他们将提供一个改进的方法，通过分子指纹早期检测和疾病的理解。该项目还将产生一种超灵敏、快速的技术，可用于个性化的护理点诊断。这些应用可以包括检测疾病标志物、病原体或确定临床样品中的蛋白质含量。这些技术将适用于一系列疾病，所有这些都将使更广泛的社区受益。