750 MHz NMR-Spectrometer for 17,6 T Magnet

用于 17.6 T 磁体的 750 MHz NMR 波谱仪

• 批准号: 514802967
• 金额: --
• 依托单位: Universität Leipzig
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2023
• 资助国家: 德国
• 起止时间: 2022-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/514802967?language=en
• 关键词: 750; MHz; NMR; Spectrometer; 17

Solid-state NMR and diffusion at the highest (in Leipzig available) magnetic fields allows to obtain information about materials not accessible at lower field due to the higher spectral resolution and sensitivity. This is of importance in multiple ways in the collaborative usage of the spectrometer. Among this, the characterization of different porous systems also in combination with adsorption or drug-release of small molecules, characterization of (para)magnetic systems as well as for aerosols the adsorption of water and processes of ice nucleation are of interest among others. At this high field also the study of diffusion of 13C species is possible.The sensitivity at highest field and the higher time resolution allows for the investigation of different effects in superconductors based on cuprates, especially measurements at high pressures with very low amount of sample (GPa-NMR). In the area of biophysics especially the structural dynamics in G-protein coupled receptors and the investigation of structure and dynamics of lipid membranes are of importance. For the latter, due to the low amount of available sample material the higher sensitivity at highest field is a prerequisite for the study.

固态核磁共振和扩散在最高（莱比锡可用）磁场允许获得有关材料的信息无法在较低的领域，由于更高的光谱分辨率和灵敏度。这在光谱仪的协作使用中以多种方式是重要的。其中，不同多孔系统的表征还结合小分子的吸附或药物释放、（帕拉）磁系统的表征以及气溶胶的水吸附和冰成核过程等都是感兴趣的。在最高场的灵敏度和更高的时间分辨率允许研究基于铜酸盐的超导体中的不同效应，特别是在高压下用非常少量的样品进行测量（GPa-NMR）。在生物物理学领域，特别是G蛋白偶联受体的结构动力学和脂膜的结构和动力学研究具有重要意义。对于后者，由于可用样品材料的量低，在最高场的较高灵敏度是研究的先决条件。