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International Data Base for Human Brain Function

国际人脑功能数据库

基本信息

批准号：
09044250
负责人：
FUKUDA Hiroshi
金额：
$ 3.65万
依托单位：
TOHOKU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for international Scientific Research
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1998
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09044250/
关键词：
Computerized Brain Atlas human brain function image database Anatomical Normalization PET MRI

项目摘要

1. Development and Evaluation of the Computerized Brain Atlas SystemWe validated the anatomical precision of spatial normalization with the Elastic Transformation System which has developed by Zilles's group with our collaboration. We found that this system shows high effectiveness in spatial normalization procedure compared with other systems, indicating that it can be used not only for positorn emission tomography (PET) activation studies but for functional magnetic resonance imaging (MRI) studies.2. Functional Brain Mapping of Cognitive and Motor FunctionRoland's group and our group participated this project. We used PET to investigate functional brain areas of humans involved in many kinds of cognitive or motor tasks. The results obtained are used as contents of the brain function database which has been developing by our group.3. Development of International Brain Anatomy DatabaseWe and Evans's group had a meeting in Montreal, and have agreed to create comparable international brain anatomy database with Zilles's group. We have decided to correct 300 3D-brain MRI of healthy subjects for each group, and to perform inter-ethnic comparisons using spatial normalization technique develped by Evans's group. Our group already corrected 150 brain MRIs, and we have estimated standard brain anatomy of the Japanese population of different age group from this data.

1.计算机脑图谱系统的开发和评估我们用Zilles团队与我们合作开发的弹性变换系统验证了空间归一化的解剖精度。我们发现，与其他系统相比，该系统在空间归一化过程中表现出较高的有效性，表明它不仅可以用于正电子发射断层扫描（PET）激活研究，而且可以用于功能性磁共振成像（MRI）研究。 2．认知和运动功能的脑功能图谱Roland课题组和我们课题组参与了这个项目。我们使用 PET 来研究人类参与多种认知或运动任务的功能性大脑区域。所得结果作为本课题组正在开发的脑功能数据库的内容。 3．国际脑解剖数据库的开发我们和Evans小组在蒙特利尔举行了会议，并同意与Zilles小组创建可比较的国际脑解剖数据库。我们决定为每组校正 300 个健康受试者的 3D 脑部 MRI，并使用 Evans 小组开发的空间归一化技术进行种族间比较。我们小组已经校正了 150 个脑部 MRI，并根据这些数据估计了日本不同年龄段人群的标准脑解剖结构。