Regulation of cellular Function by molecular chaperones
Regulation of cellular Function by molecular chaperones
批准号:
09276102
负责人:
NAGATA Kazuhiro
金额:
$54.78万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas (A)
财政年份:
1997
资助国家:
日本
项目状态:
已结题
起止时间:
1997 至 2001
中文摘要
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英文摘要
This group tried to well-organize the studies performed among three groups : "Dynamic interaction between chaperone and its substrates", "Roles of molecular chaperones in cell function" and the selected research groups from applicants.1. We held the group meeting twice a year and discussed about the progress of each research as well as perspective and direction of the whole research groups.2. We issued the "Chaperone newsletter" twice a year to stimulate the exchange of the information among the members. In addition to the 9 issues of these newsletters, we also published a special issue on "Chaperone-related ATPases". These newsletters brought broad interest and impact to general readers outside this field.3. We organized a general meeting for all the members every year and active discussion was performed on the progress of each research by the attendants including the members.4. We organized a international congress titled "Molecular Chaperone 2000" in Tokyo and two symposiums and two workshops during these 5 years.
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O.MATSUSHITA: "Substrate recognition by the collagen-binding domain of clostridium histolyticum class I collagenase."J.Biol.Chem.. 276(12). 8761-8770 (2001)
O.MATSUSHITA:“溶组织梭菌 I 类胶原酶的胶原蛋白结合结构域对底物的识别。”J.Biol.Chem.. 276(12)。
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M. TANABE: "The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing"J. Biol. Chem.. 274(39). 27845-27856 (1999)
M. TANABE:“哺乳动物 HSF4 基因通过选择性剪接产生热休克基因的激活子和阻遏子”J.
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Y. KAWAZOE: "HSF3 is a major heat shock responsive factor during chicken embryonic development"Eur. J. Biochem.. 265(2). 688-697 (1999)
Y. KAWAZOE:“HSF3 是鸡胚胎发育过程中的主要热休克反应因子”Eur。
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K.Terada, M.MORI: "The human DanJ homologue dj2 facilitates mitochondrial protein import and luciferase refolding." J.Cell Biol.139. 1089-1095 (1997)
K.Terada、M.MORI:“人类 DanJ 同源物 dj2 促进线粒体蛋白输入和荧光素酶重折叠。”
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永田和宏, 森正敬, 吉田賢右: "分子シャペロンによる細胞機能制御"シュプリンガー・フェアラーク東京. 219 (2001)
Kazuhiro Nagata、Masataka Mori、Kensuke Yoshida:“分子伴侣控制细胞功能”Springer-Verlag 东京 219 (2001)。
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共 47 条
Mechanism of the maintenance of ER homeostasis by redox regulation
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批准号:24227009
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$139.53万
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财政年份:2012
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负责人:NAGATA Kazuhiro
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Novel therapeutic strategy of ARDS by the development of Tyrosine kinase PYK2
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批准号:19590906
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2007
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负责人:NAGATA Kazuhiro
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依托单位:
Quality control mechanism of misfolded proteins
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批准号:19GS0314
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项目类别:Grant-in-Aid for Creative Scientific Research
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资助金额:$369.08万
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财政年份:2007
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负责人:NAGATA Kazuhiro
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依托单位:
Quality control mechanism for positive and negative
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批准号:16207013
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$32.12万
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财政年份:2004
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负责人:NAGATA Kazuhiro
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依托单位:
Molecular mechanism of ER-related degradation
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批准号:14037230
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$60.8万
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财政年份:2002
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负责人:NAGATA Kazuhiro
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依托单位:
Two novel chaperone-like proteins involved in ER quality control mechanism
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批准号:13308042
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$33.95万
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财政年份:2001
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负责人:NAGATA Kazuhiro
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依托单位:
Electrochemical reaction of ions in molten slags with electron in thermal plasma
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批准号:11450237
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.47万
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财政年份:1999
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负责人:NAGATA Kazuhiro
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依托单位:
New Ironmaking Method at Lower Temperature and Higher Oxygen Potential
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批准号:11355031
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$23.37万
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财政年份:1999
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负责人:NAGATA Kazuhiro
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依托单位:
Steelmaking Mechanisms for a Tatara Furnace and New Ironmaking
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批准号:09450277
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.32万
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财政年份:1997
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负责人:NAGATA Kazuhiro
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依托单位:
Removal of Copper, Zinc and Tin from Iron-based Scraps by Chlorine-Oxygen Gas Mixtures
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批准号:07555227
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$13.57万
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财政年份:1995
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负责人:NAGATA Kazuhiro
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依托单位:
Structure and function of stress proteins
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批准号:05268101
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$177.92万
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财政年份:1995
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负责人:NAGATA Kazuhiro
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依托单位:
The role of substrate-specific molecular chaperone in the trimerization of procollagen.
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批准号:07458190
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.67万
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财政年份:1995
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负责人:NAGATA Kazuhiro
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依托单位:
The role of collagen-specific molecular chaperone HSP47
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批准号:06044125
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$5.44万
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财政年份:1994
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负责人:NAGATA Kazuhiro
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依托单位:
Thermophysical Data for the Development of Mathematical Models of Solidification
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批准号:06044271
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项目类别:Grant-in-Aid for Overseas Scientific Survey.
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资助金额:$0.0万
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财政年份:1994
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负责人:NAGATA Kazuhiro
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依托单位:
Regulatory mechanism of the expression of vimentin gene during the differentiation of leukemic cells.
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批准号:05454646
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.35万
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财政年份:1993
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负责人:NAGATA Kazuhiro
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依托单位:
The role of stress proteins in the protein biosynthesis.
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批准号:04044100
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$2.88万
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财政年份:1992
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负责人:NAGATA Kazuhiro
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依托单位:
Physicochemical Study on Preparation of Oxidation-Resistant Films on High Temperature Materials and Their Oxidation Rate.
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批准号:63430013
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项目类别:Grant-in-Aid for General Scientific Research (A)
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资助金额:$0.96万
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财政年份:1988
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负责人:NAGATA Kazuhiro
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依托单位:
Biochemical and molecular biological research for the function and regultion of a collagen receptor
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批准号:61570170
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.09万
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财政年份:1986
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负责人:NAGATA Kazuhiro
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依托单位:
海外基金