Endocrinological studies on initiation of parturition in human

人类分娩起始的内分泌学研究

• 批准号: 60570787
• 负责人: MIYAKAWA Isao
• 金额: $ 1.02万
• 依托单位: Miyazaki Medical College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1985
• 资助国家: 日本
• 起止时间: 1985 至 1986
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-60570787/
• 关键词: Parturition; Initiation of labor; Prolactin; Toxemia of pregnancy

Recent years, many studies have brought greater understandings of the control of parturition in the laboratory animals. However, the endocrinological control mechanism on initiation of parturition in human has remained to be elucidated.In this project, the endocrinological studies have been done on the control of parturition in human.1.Plasma prolactin levels were measured in 21 patients with severe toxemia of pregnancy and in 111 normal pregnant women. Correlations between prolactin concentration and the severity of renal function in toxemic patients, and preterm delivery were discussed. A part of the results was reported in " Prolactin in severe toxemia of pregnancy, Eur. J. Obstet. Gynecol. Reprod. Biol., 23: 25--30, 1986." [ See reference, next page ]2." Effects of dehydroepiandrosterone sulfate ( DHA-S ) to prolactin secretion and induction of labor in term pregnant women " was studied in 1986. Various hormones ( PRL, <E_2> -17 <beta> , <E_3> , DHA-S ) were measured in nine term pregnant women who were administered 100 mg of DHA-S intravenously, and in seven pregnant women as controls. The results will be reported in " Prolactin Conference " in Tokyo in October, 1987.

近年来，许多研究使人们对实验动物的分娩控制有了更多的了解。本研究对妊娠期重度毒血症患者血浆催乳素（PRL）水平进行了测定，并与111例正常妊娠妇女进行了比较。催乳素浓度与中毒患者肾功能严重程度及早产的相关性进行了讨论。部分结果报告在“催乳素在严重妊娠毒血症，欧洲。J. Obstet.妇科Reprod.生物学：23：25- 30，1986.“[见参考资料，下一页]2。1986年研究了硫酸脱氢表雄酮（DHA-S）对足月妊娠妇女催乳素分泌和引产的影响。对<E_2><beta><E_3>9例静脉注射DHA-S 100 mg的足月妊娠妇女进行了各种激素（PRL、-17、DHA-S）测定，并以7例妊娠妇女作为对照。结果将在1987年10月在东京举行的“催乳素会议“上报告。

项目成果

Miyakawa,I., Taniyama,K., Sakata,M., Yamaguchi,M., & Mori,N.: "Prolactin in severe toxemia of pregnancy" Eur. J. Obstet. Gynecol. Reprod. Biol.23. 25-30 (1986)

宫川，I.，谷山，K.，坂田，M.，山口，M.，

Isao MIYAKAWA,et al.: Eur.J.Obstet.Gynecol.Reprod.Biol.23. 25-30 (1986)

Isao MIYAKAWA 等人：Eur.J.Obstet.Gynecol.Reprod.Biol.23。