Species and phylogenical diferences for the immunohistological properties of lymphoid postcapillary venules of some mammals

哺乳动物淋巴组织的毛细血管后小静脉（PCV）被认为是一种特殊类型的小静脉，代表淋巴细胞从血液迁移到淋巴实质的位置。我们最近的研究（M. Kimura Immunology 49:223-229 1983； M. Kimura and K. Takaya J. Electron Microsc. 33:13 3-130 1984）表明，淋巴细胞的选择性归巢是由淋巴细胞与单个淋巴器官中局部抗原的特异性相互作用决定的，并在淋巴细胞与内皮细胞，特别是各种哺乳动物淋巴组织的PCV内皮之间的相互作用水平上受到控制。本研究利用光镜和电镜观察了部分哺乳动物pcv的免疫组织学特征。在NOD小鼠胰岛病理性淋巴细胞浸润区可以观察到新形成的pcv （K. Tohya， K. Kuroiwa， R. Sugata and M. Kimura等）的有趣发现。电子显微镜1986)。

Postcapillary venules (PCV) of mammalian lymphoid tissues have been regarded as a specialized type of venule representing sites of lymphocyte migration from blood to lymphoid parenchyma. Recent our investigations (M. Kimura Immunology 49:223-229 1983; M. Kimura and K. Takaya J. Electron Microsc. 33:123-130 1984) have suggested that the selective homing of lymphocytes is determined by a specific lymphocyte interaction with localized antigen in the individual lymphoid organ and is controlled at a level of interaction between the lymphocytes and the endothelial cells, in particular the PCV endothelium of the various mammalian lymphoid tissues. In the present research project, it was to examine the immunohistological properties of some mammalian PCVs using light and electron microscopies. An interesting finding of newly forming-PCV could be obsereved in the pathological lymphocyte infiltrating region of NOD mouse pancreatic islets (K. Tohya, K. Kuroiwa, R. Sugata and M. Kimura Proc. XIth Int. Cong. Electron Microscopy 1986).