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Studies on Organ Blood Flow Using Ultrasonic Pulsed-Doppler Method in Cattle

超声脉冲多普勒法对牛器官血流的研究

基本信息

批准号：
63440017
负责人：
TOO Kimehiko
金额：
$ 14.34万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (A)
财政年份：
1988
资助国家：
日本
起止时间：
1988 至 1990
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63440017/
关键词：
Ultrasonographic diagnosis Organ blood flow Pulsed-Doppler method Bovine heart disease 牛心臓病

项目摘要

The purpose of this investigation was to : (1) develop reliable Doppler techniques to observe of organ blood flow in the kidney, hepatic vessels and cardiac cavities in the cattle, and (2) asses the potential usefulness of Doppler ultrasound to diagnosis and evaluate organ functions.1) A pulsed Doppler ultrasound scanner (EUB-450) with liner and convex type 3.5 MH_z.5.0 and 7.5 MH_z scan head was used for all examination. Ultrasound scans were performed on cattle in standing position.2) Clinically normal calves and cows were selected for investigate a basic Doppler techniques including scanning position, target organs and there vessels. In calves, the artery of the right kidney and hepatic vessels including the portal vein and intrahepatic vein, were able to detect the blood flow and the velocity. In adults, it was difficult to obtain a blood flow in the kidney because the vessel is in deep from the skin surface.3) In calves, HgCl_2 was administered to produce kidney disorder. After given the HgCl_2, velocities of blood flow in the kidney, portal vein and hepatic vein were measured for 24-30 hours. In some cases. Velocity of blood flow in the kidney was increased according to kidney lesion develop, but hepatic blood flow showed no changes. In other cases, blood flow in the kidney did not change. So, it was concluded that there is some difficulties to diagnostic evaluation of organ disorder by the blood flow.4) In cases with heart disease including dilatative cardiomyopathy and endocarditis of adult cows, the blood flow of the portal vein and hepatic vein showed decrease according to severity with congestive heart failure. From these observation, a information for early diagnosis of the disease may be Oained by measuring the hepatic blood flow.

本次调查的目的是：（1）发展可靠的多普勒技术，观察牛肾、肝血管和心腔内的器官血流，（2）评价多普勒超声在诊断和评价器官功能方面的潜在价值。1.脉冲多普勒超声扫描仪（EUB-450），线性型和凸型，3.5 MH_z.5.0和7.5 MH_z.5.0，所有检查均使用z扫描头。对站立位的牛进行超声扫描。2）选择临床正常的小牛和奶牛来研究基本的多普勒技术，包括扫描位置、靶器官和血管。在小牛中，右肾动脉和肝血管（包括门静脉和肝内静脉）能够检测血流和速度。在成年人中，由于血管位于皮肤表面的深处，很难获得肾脏中的血流。3）在小牛中，HgCl_2被施用以产生肾脏疾病。给药后24-30小时分别测定肾、门静脉和肝静脉血流速度。在某些情况下。肾血流速度随病变进展而增加，肝血流无明显变化。在其他情况下，肾脏中的血流没有变化。因此，通过血流来诊断评价器官功能障碍存在一定的困难。4）在成年奶牛的心脏病（包括充血性心肌病和心内膜炎）病例中，门静脉和肝静脉的血流根据充血性心力衰竭的严重程度而减少。通过肝血流量的测定，可为本病的早期诊断提供依据。