Isomer separation of polychlorinated aromatic compounds

多氯芳香族化合物的异构体分离

• 批准号: 01044081
• 负责人: TANAKA Nobuo
• 金额: $ 2.24万
• 依托单位: Kyoto Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for international Scientific Research
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01044081/
• 关键词: Reversed-Phase Liquid Chromatography; Electrokinetic Chromatography; Dibenzothiophene; Electrophoresis; Polychlorinated Aromatic Compound; PCB; Dioxin

Chromatographic separation of polychlorinated aromatic hydrocarbons including polychlorobiphenyls (PCBs), polychlorodibenzo-p-dioxins, and polychlorodibenzothiophenes were examined by using reversed-phase liquid chromatography and electrokinetic chromatography. The newly synthesized aromatic stationary phases such as 2-(1-pyrenyl)ethylsilylated silica gel and nitrated phenylethyl silica gel for reversed-phase liquid chromatography enabled preparative separation of all the 22 isomers of tetrachlorodibenzo-p-dioxin.Electrokinetic chromatography utilizing a fused silica capillary tubing containing an electrolyte solution afforded separation of isomers of PCBs and dioxins in the presence of water-soluble carriers such as cyclodextrins. The research program showed the usefulness of these new chromatographic methods for the separation of polychlorinated aromatic compounds of environmental concern.

用反相液相色谱和电动色谱对多氯联苯、多氯二苯并对二恶英和多氯二苯并噻吩类多氯代芳烃进行了色谱分离。新合成的芳香族固定相，如2-(1-戊烯基)乙基硅胶和硝化苯乙基硅胶，可用于反相色谱分离四氯二苯并对二恶英的全部22个异构体。电动色谱柱使用含有电解质溶液的熔融石英毛细管，在环糊精等水溶性载体的存在下，实现了多氯联苯和二恶英的异构体分离。该研究项目展示了这些新的层析方法在分离环境关注的多氯芳香族化合物方面的有效性。

项目成果

田中信男: "液体クロマトグラフィ-による芳香族塩素化合物異性体の分離" 環境.

Nobuo Tanaka：“通过液相色谱法分离芳香氯化合物异构体”环境。

K. Kimata, K. Hosoya, N. Tanaka, T. Araki, E. Barnhart, D. G. Patterson, S. Terabe,: "A newly developed stationary phase, nitrated phenylethyl silica gel, and HPLC separation of 1,2,4,6-/1,2,4,9-TCDD isomer pair" J. High Resolut. Chromatogr.13. 137-138 (1

K. Kimata、K. Hosoya、N. Tanaka、T. Araki、E. Barnhart、D. G. Patterson、S. Terabe，：“新开发的固定相，硝化苯乙基硅胶，以及 1、2、4 的 HPLC 分离，

E.R.Barnhart: "HPLC elution order of positional isomers of hexachloro-biphenyl with octadecyl-,pyrenylethyl-,and naphthylethyl silylated silica gel as stationary phase" J.Chromatography.

E.R.Barnhart：“以十八烷基、芘基乙基和萘乙基甲硅烷基化硅胶为固定相的六氯联苯位置异构体的 HPLC 洗脱顺序”J.Chromatography。

S. Terabe, Y. Miyashita, O. Shibata, E. R. Barnhart, L. R. Alexander, D. G. Patterson, B. L. Karger, K. Hosoya, N. Tanaka,: "Separation of highly hydrophobic compounds by cyclodextrin modified micellar electrokinetic chromatography." J. Chromatogr.

S. Terabe、Y. Miyashita、O. Shibata、E. R. Barnhart、L. R. Alexander、D. G. Patterson、B. L. Karger、K. Hosoya、N. Tanaka，：“通过环糊精改性胶束电动色谱法分离高度疏水性化合物。”

N. Tanaka, K. Hosoya, Y. Tachibana, M. Araki, K. Tanaka, A. Kaji,: "Selectivity of 2-(1-pyrenyl)ethylsilylated silica gel in the isomer separation of cyclohexane derivatives." J. Chromatogr. Sci.,. 27. 735-740 (1989)

N. Tanaka、K. Hosoya、Y. Tachibana、M. Araki、K. Tanaka、A. Kaji，：“2-(1-芘基)乙基甲硅烷基化硅胶在环己烷衍生物异构体分离中的选择性”。