Isomer separation of polychlorinated aromatic compounds

用反相液相色谱和电动色谱对多氯联苯、多氯二苯并对二恶英和多氯二苯并噻吩类多氯代芳烃进行了色谱分离。新合成的芳香族固定相，如2-(1-戊烯基)乙基硅胶和硝化苯乙基硅胶，可用于反相色谱分离四氯二苯并对二恶英的全部22个异构体。电动色谱柱使用含有电解质溶液的熔融石英毛细管，在环糊精等水溶性载体的存在下，实现了多氯联苯和二恶英的异构体分离。该研究项目展示了这些新的层析方法在分离环境关注的多氯芳香族化合物方面的有效性。

Chromatographic separation of polychlorinated aromatic hydrocarbons including polychlorobiphenyls (PCBs), polychlorodibenzo-p-dioxins, and polychlorodibenzothiophenes were examined by using reversed-phase liquid chromatography and electrokinetic chromatography. The newly synthesized aromatic stationary phases such as 2-(1-pyrenyl)ethylsilylated silica gel and nitrated phenylethyl silica gel for reversed-phase liquid chromatography enabled preparative separation of all the 22 isomers of tetrachlorodibenzo-p-dioxin.Electrokinetic chromatography utilizing a fused silica capillary tubing containing an electrolyte solution afforded separation of isomers of PCBs and dioxins in the presence of water-soluble carriers such as cyclodextrins. The research program showed the usefulness of these new chromatographic methods for the separation of polychlorinated aromatic compounds of environmental concern.