A Genetic Study on the Dento-Facial Growth by the Twin Study Method.

双胞胎研究法对牙面部生长的遗传学研究。

• 批准号: 01440081
• 负责人: NAKATA Minoru
• 金额: $ 11.07万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (A)
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1991
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01440081/
• 关键词: Oral-Facial Genetics; Growth; Twin study method; 歯顎顔面の遺伝; 成長発育; 双生児

The aim of this investigation was to search the genetic contribution to the growth of dento-facial complex. In order to accomplish this, the application of the twin study method is most efficient to detect the relative contribution of the heredity a13EA\ : nd the einvironment to the inter-individual variations among the sample population. In this study the dental casts and the roentogeno-cephalograms of the twins were collected from the Department of Pediatric Dentistry of Kyushu University Dental Hos13EA\ : pital and from the samples registred at the Department of Pedodontics of Tokyo Medical & Dental University school of Dentistry. The morphology of tooth crown and the dental arch were measured with the three dimensional procedure. The size and morpho13EA\ : logy of the cranio-facial complex was measured two-dimensionally. These data were feeded into the computer to keep the data file and to analyze the similarity of dento-facial growth of twins to compare between the identical twin pairs and the frater13EA\ : nal twin pairs.As a results it is indicated that the dento-facial growth is strongly influenced by the genetic factors.

这项研究的目的是寻找基因对牙齿-面部复合体生长的贡献。为了实现这一点，应用双生子研究法是最有效地检测遗传和环境对样本群体个体间变异的相对贡献。这对双胞胎的牙模和X线片来自九州大学牙科大学附属医院儿童牙科和东京医科大学牙科学院牙科学部登记的标本。对牙冠、牙弓进行三维测量。对颅面复合体的大小和形态进行了二维测量。将这些数据输入计算机保存数据文件，并分析双胞胎牙齿生长的相似性，以比较同卵双胞胎和异卵双胞胎的牙齿生长情况。结果表明，牙齿生长受遗传因素的影响很大。

项目成果

緒方 哲朗: "第2乳臼歯咬耗量の3次元的定量化について第1報 計測方法と測定精度について" 下顎運動機能とEMG論文集. 9. 49-52 (1991)

Tetsuro Ogata：“关于第二乳磨牙磨损量的三维量化、测量方法和测量精度的首次报告”Journal of Mandibular Motor Function and EMG 9. 49-52 (1991)。

早崎治明・山崎要一・中田稔: "小児の下顎前方滑走運動に関する研究" 小児歯誌. 29(2). 379-388 (1991)

Haruaki Hayasaki、Yoichi Yamazaki、Minoru Nakata：“儿童下颌骨向前滑动运动的研究”《儿科牙科杂志》29(2) 379-388 (1991)。

竹中 稔,緒方 哲朗,小田 博,早崎 治明,阿部 和久,中田 稔: "第一大四歯萌出前後における乳歯咬合小面の三次元的推移に関する研究" 小児歯誌. 28. 313-326 (1990)

Minoru Takenaka、Tetsuro Ogata、Hiroshi Oda、Haruaki Hayasaki、Kazuhisa Abe、Minoru Nakata：“前四颗牙齿萌出前后乳牙咬合面的三维转变研究”《儿童牙科杂志》28。 313-326（1990）

Nonaka,K.et al: "Genetic study of mandibularsize and Shape in rats." Pediatric Dental Journal. 1(1). 27-35 (1991)

Nonaka,K.et al：“大鼠下颌大小和形状的遗传研究”。

緒方哲朗,中田稔: "オクル-ザルプレスケ-ルを用いた咬合接触面測定システムの改良とその有効性について" 小児歯科学雑誌. 28(1). (1990)

Tetsuro Ogata、Minoru Nakata：“使用咬合预标尺改进咬合接触面测量系统及其有效性”《儿科牙科杂志》28(1) (1990)。