Development of a New Ambulatory Monitoring System for Indirect Beat-to-Beat Arterial Blood Pressure Using the Volume-compensation Method

使用容量补偿法开发新型间接逐搏动脉血压动态监测系统

• 批准号: 01850083
• 负责人: YAMAKOSHI Ken-ichi
• 金额: $ 3.07万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B).
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01850083/
• 关键词: Volume-compensation Method; Indirect Sphygmomanometry; Instantaneous Arterial Pressure; Superficial Temporal Artery; Ambulatory Monitoring; Pneumatic Servo-control System; Photoelectric Plethysmography; Electro-pneumatic Converter

A new portable instrument for the ambulatory monitoring of instantaneous arterial blood pressure using the volume-compensation method previously proposed by us has been developed in the first project year. The superficial temporal artery was chosen as a measuring site order to minimize restraint for a subject and to avoid venous congestion during the long-term monitoring. A disc-type cuff with a reflectance-type photo-sensor for blood volume detection was firmly placed to the subject's head using a belt and the subject carried a cuff-pressure (Pc) control (CPC) unit (32x65x110mm, 210g) and a microprocessor-based central processing & recording (MCPR) unit (85x185x200mm, 800g). An interactive software was also developed in this year for sequential measurement control and data storage in an automatic manner during the monitoring. The CPC unit consisted mainly of a micro air pump for compressed air supply and a miniature piezo-electric valve (PVAA8000120H, JUPITOR Co.) for Pc control. The … More MCPR unit performs the automatic setting of the servo-reference value and control of the servo-gain, processing and storing of beat-to-beat indirect systolic (Pcs), mean (Pcm) and diastolic blood pressure (Pcd) and instantaneous heart rate (HR). Altogether 60,000 beats of each data can be stored in a memory IC unit. After the monitoring, the stored data are reproduced and analyzed using a conventional personal computer or a specially ordered equipment for data analysis (ECM-1DS, ESCOM CO.) to obtain trend charts and histograms of Pcs, Pcm, Pcd and HR.In the second project year, the instrument was further improved as follows and the performance in an operation was evaluated through the clinical and dieldwork experiments. A nozzle-flapper type miniature electro-pneumatic converter for Pc control was newly designed, which was installed in the disc-type cuff together with a miniature pressure toansducer for Pc measurement. Through these modification, the frequency response of the Pc servocontrol system was highly and only the improved MCPR unit including a micro-air pump was carried by a subject. In order to evaluate the accuracy for blood pressure measurement by this instrument, simultaneous measurements of direct brachial and indirect superficial temporal arterial pressure were made in catheterised patients, showing fairly good agreements between these two values and pressure wave forms. With this instrument, ambulatory monitorings during fieldwork, highway driving, physicotherapeutics and so on, were successfully carried out, revealing that the instrument seems to have good operating performances and to be an useful means to monitor instantaneous variations of blood pressure in unrestricted subjects. Because the superficial temporal artery was adopted as a measuring site, the long-term monitoring could be made in the subjects being little affected by discomfort.The whole programs of this research project were completed within the project term with satisfactory results as described above. Less

在第一年，已开发了一种使用美国先前提出的体积补偿方法对瞬时人工体血压进行门诊监测的新型便携式工具。选择浅表临时人工制品作为测量现场顺序，以最大程度地减少对受试者的限制，并在长期监测期间避免静脉充血。首先使用皮带将带有反射率类型的光音量检测的圆盘式袖带使用皮带将受试者的头部放置在受试者的头上，受试者携带袖口压力（PC）控制（CPC）单元（32x65x110mm，210G）和基于微处理器的中央处理和记录（MCPR）单位（MCPR）单元（85x185x185x200mmm，800G00G）。今年还开发了一个交互式软件，用于在监视过程中以自动方式进行顺序测量控制和数据存储。 CPC单元主要由用于压缩空气供应的微型气泵和用于PC控制的微型压电阀（PVAA8000120H，Jupitor Co.）。 …更多的MCPR单元执行伺服增益的伺服引用值的自动设置，处理和存储Beat-Beat间接收缩期（PC），平均（PCM）和舒张压（PCD）和瞬时心脏速率（HR）。总共可以将60,000个数据存储在内存IC单元中。监视后，使用常规的个人计算机或专门订购的数据分析设备（ECM-1DS，ESCOM CO。）复制并分析了存储的数据，以获取PCS，PCM，PCM，PCD和HR.IN的趋势图表和直方图，第二年，该仪器在以下操作中得到了进一步改进，并且通过Cline Cline and Dieldworks的运营进行了进一步的效果。新设计的用于PC控制的喷嘴 - 燃烧器型微型电动转换器是新设计的，它安装在圆盘式袖带中，以及用于PC测量的微型压力toansducer。通过这些修改，PC伺服控制系统的频率响应高度高，只有受试者携带了包括微空气泵在内的改进的MCPR单元。为了评估该仪器血压测量的准确性，在导管插入的患者中进行了简单的直接臂和间接表面临时动脉压的简单测量，显示了这两个值和压力波形之间的相当良好的协议。使用该仪器，在现场工作，高速公路驾驶，物理治疗等期间的卧床监测得到了成功进行的，表明该仪器似乎具有良好的操作性能，并且是监测无限制受试者血压瞬时变化的有用手段。由于浅表临时动脉被用作测量部位，因此可以对受试者进行长期监测，这几乎不受不适的影响。该研究项目的整个程序在项目期限内完成，并如上所述满意厂结果。较少的

项目成果

YAMAKOSHI, Ken-ichi: "New non-invasive arterial pressure measurements : Volume-oscillometric & volume-compensation method for measuring finger arterial pressure" Journal of Clinical and Experimental Medicine. 153(13). 818-824 (1990)

YAMAKOSHI, Ken-ichi：“新的无创动脉压测量：容量示波法

KAWARADA, Atsushi et al.: "Ambulatory monitoring of indirect beat-to-beat arterial pressure in human fingers by a volume-compensation method" Medical & Biological Engineering & Computing. 29. 55-62 (1991)

KAWARADA、Atsushi 等人：“通过容量补偿方法动态监测人类手指的间接逐搏动脉压” 医疗

山越 憲一: "新しい血圧測定法" 医学のあゆみ. 153. 818-824 (1990)

Kenichi Yamakoshi：“新血压测量方法”医学史 153. 818-824 (1990)。

山越憲一: "非観血的血圧測定法" 臨床モニタ. 1. 39-51 (1990)

Kenichi Yamakoshi：“无创血压测量方法”临床监测 1. 39-51 (1990)。

A.Kawarada et al.: "Ambulatory monitoring of indirect beatーtoーbeat arterial pressure in human fingers by a volumeーcompensation method" Med. & Biol. Eng. & Comput.29. 55-62 (1991)

A. Kawarada 等人：“通过容量补偿方法动态监测人类手指的逐搏动脉压”Med & Biol & Comput.29 (1991)。