Development of a New Ambulatory Monitoring System for Indirect Beat-to-Beat Arterial Blood Pressure Using the Volume-compensation Method

使用容量补偿法开发新型间接逐搏动脉血压动态监测系统

• 批准号: 01850083
• 负责人: YAMAKOSHI Ken-ichi
• 金额: $ 3.07万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B).
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01850083/
• 关键词: Volume-compensation Method; Indirect Sphygmomanometry; Instantaneous Arterial Pressure; Superficial Temporal Artery; Ambulatory Monitoring; Pneumatic Servo-control System; Photoelectric Plethysmography; Electro-pneumatic Converter

A new portable instrument for the ambulatory monitoring of instantaneous arterial blood pressure using the volume-compensation method previously proposed by us has been developed in the first project year. The superficial temporal artery was chosen as a measuring site order to minimize restraint for a subject and to avoid venous congestion during the long-term monitoring. A disc-type cuff with a reflectance-type photo-sensor for blood volume detection was firmly placed to the subject's head using a belt and the subject carried a cuff-pressure (Pc) control (CPC) unit (32x65x110mm, 210g) and a microprocessor-based central processing & recording (MCPR) unit (85x185x200mm, 800g). An interactive software was also developed in this year for sequential measurement control and data storage in an automatic manner during the monitoring. The CPC unit consisted mainly of a micro air pump for compressed air supply and a miniature piezo-electric valve (PVAA8000120H, JUPITOR Co.) for Pc control. The … More MCPR unit performs the automatic setting of the servo-reference value and control of the servo-gain, processing and storing of beat-to-beat indirect systolic (Pcs), mean (Pcm) and diastolic blood pressure (Pcd) and instantaneous heart rate (HR). Altogether 60,000 beats of each data can be stored in a memory IC unit. After the monitoring, the stored data are reproduced and analyzed using a conventional personal computer or a specially ordered equipment for data analysis (ECM-1DS, ESCOM CO.) to obtain trend charts and histograms of Pcs, Pcm, Pcd and HR.In the second project year, the instrument was further improved as follows and the performance in an operation was evaluated through the clinical and dieldwork experiments. A nozzle-flapper type miniature electro-pneumatic converter for Pc control was newly designed, which was installed in the disc-type cuff together with a miniature pressure toansducer for Pc measurement. Through these modification, the frequency response of the Pc servocontrol system was highly and only the improved MCPR unit including a micro-air pump was carried by a subject. In order to evaluate the accuracy for blood pressure measurement by this instrument, simultaneous measurements of direct brachial and indirect superficial temporal arterial pressure were made in catheterised patients, showing fairly good agreements between these two values and pressure wave forms. With this instrument, ambulatory monitorings during fieldwork, highway driving, physicotherapeutics and so on, were successfully carried out, revealing that the instrument seems to have good operating performances and to be an useful means to monitor instantaneous variations of blood pressure in unrestricted subjects. Because the superficial temporal artery was adopted as a measuring site, the long-term monitoring could be made in the subjects being little affected by discomfort.The whole programs of this research project were completed within the project term with satisfactory results as described above. Less

在项目的第一年，我们开发了一种新型便携式仪器，用于使用我们之前提出的容量补偿方法动态监测瞬时动脉血压。选择颞浅动脉作为测量部位，以尽量减少对受试者的束缚，并避免长期监测期间静脉充血。使用带子将带有用于血容量检测的反射型光传感器的圆盘型袖带牢固地放置在受试者的头部，并且受试者携带袖带压力（Pc）控制（CPC）单元（32x65x110mm，210g）和基于微处理器的中央处理和记录（MCPR）单元（85x185x200mm，800g）。今年还开发了交互式软件，用于在监测过程中自动进行顺序测量控制和数据存储。 CPC装置主要由用于压缩空气供应的微型气泵和用于PC控制的微型压电阀（PVAA8000120H，JUPITOR Co.）组成。 MCPR 装置自动设置伺服参考值并控制伺服增益，处理和存储逐次间接收缩压 (Pcs)、平均血压 (Pcm) 和舒张压 (Pcd) 以及瞬时心率 (HR)。每个数据总共可存储 60,000 个心跳，存储在一个存储 IC 单元中。监测结束后，使用传统的个人计算机或专门订购的数据分析设备（ECM-1DS，ESCOM CO.）对存储的数据进行再现和分析，以获得Pcs、Pcm、Pcd和HR的趋势图和直方图。在第二个项目年，仪器进一步改进如下，并通过临床和模具实验评估手术中的性能。新设计了一种用于Pc控制的喷嘴挡板式微型电空转换器，与用于Pc测量的微型压力传感器一起安装在圆盘式袖带中。通过这些修改，PC伺服控制系统的频率响应很高，并且只有包含微型气泵的改进MCPR单元被主体携带。为了评估该仪器测量血压的准确性，对插管患者同时测量了直接肱动脉压和间接颞浅动脉压，结果显示这两个值和压力波形之间具有相当好的一致性。利用该仪器成功地进行了野外作业、高速公路驾驶、理疗等过程中的动态监测，表明该仪器具有良好的操作性能，是监测不受限制的受试者血压瞬时变化的有用手段。由于采用颞浅动脉作为测量部位，可以对受测者进行长期监测，受不适影响较小。本研究项目的全部方案均在项目期限内完成，取得了满意的效果。较少的

项目成果

YAMAKOSHI, Ken-ichi: "New non-invasive arterial pressure measurements : Volume-oscillometric & volume-compensation method for measuring finger arterial pressure" Journal of Clinical and Experimental Medicine. 153(13). 818-824 (1990)

YAMAKOSHI, Ken-ichi：“新的无创动脉压测量：容量示波法

KAWARADA, Atsushi et al.: "Ambulatory monitoring of indirect beat-to-beat arterial pressure in human fingers by a volume-compensation method" Medical & Biological Engineering & Computing. 29. 55-62 (1991)

KAWARADA、Atsushi 等人：“通过容量补偿方法动态监测人类手指的间接逐搏动脉压” 医疗

山越 憲一: "新しい血圧測定法" 医学のあゆみ. 153. 818-824 (1990)

Kenichi Yamakoshi：“新血压测量方法”医学史 153. 818-824 (1990)。

山越憲一: "非観血的血圧測定法" 臨床モニタ. 1. 39-51 (1990)

Kenichi Yamakoshi：“无创血压测量方法”临床监测 1. 39-51 (1990)。

A.Kawarada et al.: "Ambulatory monitoring of indirect beatーtoーbeat arterial pressure in human fingers by a volumeーcompensation method" Med. & Biol. Eng. & Comput.29. 55-62 (1991)

A. Kawarada 等人：“通过容量补偿方法动态监测人类手指的逐搏动脉压”Med & Biol & Comput.29 (1991)。