A Glycobiology Facility for Glycoconjugate Analysis and Oligosaccharide Sequencing

用于糖复合物分析和寡糖测序的糖生物学设施

• 批准号: LE0454209
• 负责人: Prof Brett Garner
• 金额: $ 8.42万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-03-11 至 2005-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0454209
• 关键词: Glycobiology; Facility; Glycoconjugate; Analysis; Oligosaccharide

The carbohydrate moiety of glycoconjugates plays an important role in their function and metabolism. Advances in glycan analytical and oligosaccharide sequencing techniques offer tremendous potential for the application of glycobiology to biotechnology, cell biology and medicine. This application aims to establish a Glycobiology Facility dedicated to glycoconjugate analysis and oligosaccharide sequencing. Funds are requested for state of the art HPLC equipment, associated equipment and reagents for glycan purification/labelling, and a staff member, that are all essential to establish this technology in Australia. The Facility will support $25 million of existing research; approximately half of which is derived from ARC.

糖缀合物的碳水化合物部分在其功能和代谢中起重要作用。聚糖分析和寡糖测序技术的进步为糖生物学在生物技术、细胞生物学和医学中的应用提供了巨大的潜力。本申请旨在建立一个专门用于糖缀合物分析和寡糖测序的糖生物学设施。要求提供资金，以购置最先进的高效液相色谱设备、相关设备和聚糖纯化/标记试剂以及一名工作人员，这些都是在澳大利亚建立这一技术所必不可少的。该基金将支持2 500万美元的现有研究，其中大约一半来自ARC。