A Glycobiology Facility for Glycoconjugate Analysis and Oligosaccharide Sequencing

糖结合物的碳水化合物部分在它们的功能和代谢中起着重要作用。糖链分析和寡糖测序技术的进步为糖生物学在生物技术、细胞生物学和医学中的应用提供了巨大的潜力。这项申请旨在建立一个专门从事糖共轭分析和寡糖测序的糖生物学设施。需要资金用于在澳大利亚建立这项技术所必需的最先进的高效液相色谱设备、相关设备和葡聚糖纯化/标签试剂以及一名工作人员。该基金将支持2500万美元的现有研究；其中约一半来自ARC。

The carbohydrate moiety of glycoconjugates plays an important role in their function and metabolism. Advances in glycan analytical and oligosaccharide sequencing techniques offer tremendous potential for the application of glycobiology to biotechnology, cell biology and medicine. This application aims to establish a Glycobiology Facility dedicated to glycoconjugate analysis and oligosaccharide sequencing. Funds are requested for state of the art HPLC equipment, associated equipment and reagents for glycan purification/labelling, and a staff member, that are all essential to establish this technology in Australia. The Facility will support $25 million of existing research; approximately half of which is derived from ARC.