课题基金 / 基金详情

Defining the mechanisms by which ABCA7 and apoE control Alzheimer's disease risk. Functional characterisation of new therapeutic targets for dementia prevention and treatment.

Defining the mechanisms by which ABCA7 and apoE control Alzheimer's disease risk. Functional characterisation of new therapeutic targets for dementia prevention and treatment.
定义 ABCA7 和 apoE 控制阿尔茨海默病风险的机制。
批准号:
nhmrc : GNT1109831
负责人:
Prof Brett Garner
金额:
$68.8万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --

项目摘要

项目成果

Prof Brett Garner的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Alzheimer’s disease (AD) is the major cause of dementia and is currently without a curative treatment. An understanding of the pathways that lead to AD is urgently required to develop approaches for treatments. We have discovered new pathways by which proteins called ApoE and ABCA7 control AD. We now aim to define precisely how these proteins work in the brain and use this information to develop therapeutic approaches to treat AD in humans.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Defining the mechanisms by which ABCA7 and apoE control Alzheimer's disease risk. Functional characterisation of new therapeutic targets for dementia prevention and treatment.
  • 批准号:
    nhmrc : 1109831
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $47.43万
  • 财政年份:
    2016
  • 负责人:
    Prof Brett Garner
  • 依托单位:
Lysosomal dysfunction as an inhibitor of vitamin B12 utilisation in neurodegenerative diseases
  • 批准号:
    nhmrc : 1065982
  • 项目类别:
    Project Grants
  • 资助金额:
    $37.0万
  • 财政年份:
    2014
  • 负责人:
    Prof Brett Garner
  • 依托单位:
A novel intracellular roadblock to cobalamin utilization in ageing and Alzheimer�s disease
  • 批准号:
    nhmrc : 1047848
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $0.75万
  • 财政年份:
    2013
  • 负责人:
    Prof Brett Garner
  • 依托单位:
Cellular effects of glucocerebrosidase (GBA) mutations in Lewy body diseases
  • 批准号:
    nhmrc : 1008307
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $35.0万
  • 财政年份:
    2011
  • 负责人:
    Prof Brett Garner
  • 依托单位:
国内基金
海外基金
Exploring the Intrinsic Mechanisms of CEO Turnover and Market
  • 批准号:
    --
  • 项目类别:
    外国学者研究基金
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    HAOFEI Z
  • 依托单位:
Exploring the Intrinsic Mechanisms of CEO Turnover and Market Reaction: An Explanation Based on Information Asymmetry
  • 批准号:
    W2433169
  • 项目类别:
    外国学者研究基金项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    HAOFEI ZHANG
  • 依托单位:
Erk1/2/CREB/BDNF通路在CSF1R相关性白质脑病致病机制中的作用研究
  • 批准号:
    82371255
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2023
  • 负责人:
    曹立
  • 依托单位:
Foxc2介导Syap1/Akt信号通路调控破骨/成骨细胞分化促进颞下颌关节骨关节炎的机制研究
  • 批准号:
    82370979
  • 项目类别:
    面上项目
  • 资助金额:
    48.00万元
  • 批准年份:
    2023
  • 负责人:
    张善勇
  • 依托单位: