Trial of enhancement in lyngbatic organ activety during TPN using PSK

点击翻译按钮获取中文摘要

In 1991, we made a study of the influence of the method of feeding by central venous catheter, and obtained the following results.1)The method of feeding by central venous catheter causes the atrophy of the mucus of the digestive tract.2)Dosage of PSK prevents the decrease of agmen peyerianum and also normalizes the internal distribution of immunological cells.In 1992, we studied how the method of feeding by central venous catheter (in TPN group) affects the immunological system.1)S-IgA in gall2)S-IgA in portal venous blood3)Bacterial translocation to mesenteric lymph nodes respectively studied.ResultsThe bacteriological study of mesenteric lymph nodes revealed that bacteria were detected at a higher rate in TPN group compared with the control groupThere was no difference in endotoxin concentration in portal venous blood.Less S-IgA was detected in gall and portal venous blood in TPN group.In the study of distribution of immunological cells in the mucus of digestive tract, the test result implied a fall in immunocompetence in TPN group.Conclusion/reviewThe immunocompetence at digestive tract was lowered by using TPN for a long term. The dosage of BRM such as PSK is effective against these falls.