Research project on the varient modification of thermosensitivity in the
Research project on the varient modification of thermosensitivity in the
批准号:
04304029
负责人:
KOSAKA Mitsuo
金额:
$10.88万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Co-operative Research (A)
财政年份:
1992
资助国家:
日本
项目状态:
已结题
起止时间:
1992 至 1994
中文摘要
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英文摘要
The present Research project on the varient modification of thermosensitivity in the cellular and bodily level is characterized by the interdisciplinary research fields that are composed of 8 Environmental physiologists, 3 Radiation Biologist, 2 Molecular Biologists and 3 Neuro-physiologists.1.The essential problems concerned with themosenstivity as well as with thermo-tolerance of cellular function were analyized from the view points of themoregulatory, febrile, sweating, immunological, endocrinological, cellular, and molecular biological levels.2.The thermoregulatory set-point and its modication of the varient neuro-peptides such like neurotensin, bombesin, neuropeptide Y.calcitonin gene-related peptide (CGRP) were reported by the present Environmental physiologists.3.Thermosensitivity and thermotolerance are modified not only by the above-mentioned neuropeptides but also the variant cytokines such like IL-1alpha beta, Heat Shock Proteins (HSP70,47), Quercetin(Suppressor of HSP induction) and LPS-pyrogen which were reported by radiation and molecular Biologists.
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Ohtsuka K.: "Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ." Blochem Biophys Res Comm. 197. 235-240 (1993)
Ohtsuka K.:“热休克蛋白 hsp40 的 cDNA 克隆,它是细菌 DnaJ 的人类同源物。”
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黒島 晨汎 他: "非温熱性刺激による褐色脂肪組織内ガングリオシドGM_3の変化" 第70回日本生理学会大会予稿集. 294 (1993)
Akihiro Kuroshima 等人:“非热刺激导致棕色脂肪组织中神经节苷脂 GM_3 的变化”第 70 届日本生理学会年会论文集 294 (1993)。
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Ohtsuka K.: "Effect of ATP on the release of hsp70 and hsp40 from the nucleus in heat-shocked HeLa cells." Exptl Cell Res. 209. 357-366 (1993)
Ohtsuka K.:“ATP 对热休克 HeLa 细胞细胞核中 hsp70 和 hsp40 释放的影响。”
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小坂光男 他: "放射鼓膜温計の基本的・臨床的検討" 日生気誌. 29(2). 119-125 (1992)
Mitsuo Kosaka 等:“辐射鼓膜温度计的基础和临床研究”Nissei Kishi 29(2) 119-125 (1992)。
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Kosaka,M.et al.: "High Altitude Medicine" ed by G.Ueda et al.,published by Shin Shu University Press Matsumoto,Japan, 546 (1992)
Kosaka,M.et al.:“高海拔医学”,G.Ueda 等人编辑,信州大学出版社出版,松本,日本,546 (1992)
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共 29 条
Analysis of sweating of human skin transplanted on the weak immune mouse
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批准号:10470018
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.38万
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财政年份:1998
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负责人:KOSAKA Mitsuo
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依托单位:
Study on sweating from xenotransplanted human skin
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批准号:08407003
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$6.14万
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财政年份:1996
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负责人:KOSAKA Mitsuo
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依托单位:
Basic research on development of experimental animal model for weak heat tolerance and bbehavioral thermoregulation
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批准号:06557007
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$11.84万
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财政年份:1994
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负责人:KOSAKA Mitsuo
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依托单位:
Induction of Heat Shock Proteins (HSPs) in the Process of Heat Tolerance
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批准号:01480134
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.35万
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财政年份:1989
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负责人:KOSAKA Mitsuo
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依托单位:
Analysis of thermoregulatory and pyretic responses in heat-and cold-acclimation
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批准号:62480116
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.97万
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财政年份:1987
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负责人:KOSAKA Mitsuo
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依托单位:
Analysis of thermoregulatory responses in the process of heat-and cold-acclimatization
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批准号:60480122
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.52万
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财政年份:1985
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负责人:KOSAKA Mitsuo
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依托单位:
海外基金