Subtypes of Nociceptors in the Oral region.

点击翻译按钮获取中文摘要

Properties of nociceptors of skin have been extensively investigated, however, less is known about the characteristics of nociceptive afferents that innervate mucosal areas. In the present review, recent studies of the nociceptors in the oral mucosa are summarized. Oral mucosal nociceptors has different properties from the skin nociceptors. This means quite important for detection of nociceptive stimulus which applied during daily food intake. In addition, some of the mucosal nociceptors were also excited by bitter solution, suggesting that these nociceptors in the oral mucosa play a significant role in production of taste sensation by irritant foods. Tooth pulpal and periodontal nociceptors were also investigated, showing that distributions of nociceptors are different among these structures.