Research on the Development of Porous Implant Material for Organisms by Utilizing Inorganic Powder

利用无机粉体开发多孔生物植入材料的研究

• 批准号: 12650728
• 负责人: SAKAMOTO Takashi
• 金额: $ 1.09万
• 依托单位: Yatsushiro National College of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12650728/
• 关键词: implant; powder sintering; titanium powder; SPS; spark plasma sintering

The use of implant materials capable of replacing the bones and joints of the human body is increasing. Recently, a method has been developed in which a porous material is inserted between the bones, and the new bone is grown in the pores of the material.This research used titanium (Ti) that is considered inactive to organisms, and created an implant material by sintering the Ti material utilizing a spark plasma sintering (SPS) method. As a result of examining the conditions for preparation of the implant material, the following conclusions were obtained.(1) By fixing Ti particles to a core Ti rod followed by sintering them using the SPS method, an implant material was successfully prepared.(2)Junction among Ti materials sufficiently proceeded depending on sintering conditions, and the material with targeted junction and structure such as sufficient shear strength and porosity was obtained.(3) As a result of sintering sole Ti particles for the purpose of miniaturizing the implant material, a small implant material 5 mm in diameter made of pure Ti particles was created.(4) The observation of its cross-sectional structure showed good junction rate, porosity, and neck size, which verified that the targeted porous implant material was successfully obtained.

能够替代人体骨骼和关节的植入材料的使用正在增加。近年来，开发了在骨间插入多孔性材料，使新骨在该材料的细孔内生长的方法，本研究使用对生物体无活性的钛（Ti），通过放电等离子烧结（SPS）法烧结Ti材料，制作了植入体材料。作为检查植入物材料制备条件的结果，获得以下结论。(1)通过将钛颗粒固定到核心钛棒上，然后使用SPS方法对其进行烧结，成功制备了植入材料。（2）根据烧结条件，Ti材料之间的接合充分进行，并且获得具有目标接合和结构的材料，例如足够的剪切强度和孔隙率。(3)为了使植入物材料致密化而烧结唯一的Ti颗粒，因此产生了由纯Ti颗粒制成的直径为5 mm的小植入物材料。(4)其横截面结构观察显示良好的连接率、孔隙率和颈部尺寸，证实成功获得了目标多孔植入材料。

项目成果

石田, 山本, 浅川, 坂本: "スッポン甲羅・腹甲粉末によるラット肝臓障害抑制"熊本大学教育学部紀要. 51号. 127-133 (2002)

Ishida、Yamamoto、Asakawa、Sakamoto：“粉状鳖甲和腹甲对大鼠肝脏损伤的抑制”熊本大学教育学部通报 51, 127-133 (2002)。

坂本 卓: "おもしろ話で理解する機械工学入門"日刊工業新聞社. 198 (2001)

坂本卓：“通过有趣的故事介绍机械工程”日刊工业新闻社 198 (2001)。

坂本卓: "おもしろ話で理解する金属材料入門"日刊工業新聞社. 198 (2000)

坂本隆：《通过有趣的故事了解金属材料》日刊工业新闻社198（2000）。

坂本 卓: "おもしろ話で理解する金属材料入門"日刊工業新聞社. 198 (2000)

坂本拓：“通过有趣的故事介绍金属材料”日刊工业新闻社198（2000）。

坂本卓: "おもしろ話で理解する製図学入門"日刊工業新聞社. 181 (2002)

坂本隆：“通过有趣的故事介绍起草”日刊工业新闻社181（2002）。