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Trial construction of birthweight and birth length references for multiple birth neonates in Japan.

日本多胞胎新生儿出生体重和出生身长参考的试验构建。

基本信息

批准号：
13670407
负责人：
KATO Noriko
金额：
$ 0.9万
依托单位：
National Institute of Public Health
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2002
项目状态：
已结题

项目摘要

In Japan, birth, death, and stillbirth certificates are currently stored in data files on magnetic tapes. These certificates are filed in the city health department and changed into computerized files in Ministry of Health, Labour and Welfare of Japan. This database contains sex, birthweight, gestational age, parity, ages of father and mother.Pairs of multiple births were identified by birthplace, the ages of the parents, gestational age, and the year and month of birth; The birthweight of twins from multiparous mothers was greater than those from primiparous mothers. Our results can be used for assessment of birthweight of multiple births in Japan.The median birth length according to gestational age was found to be the greatest in twins, lower in triplets and the lowest in quadruplets, Birth length of twins was shorter than singletons, but difference was smaller than that of birthweight between twins and singletons. Multiple birth neonates showed asymmetrical growth.Perinatal mortality was compared by categories of bithweight and gestational age, for twins and triplets versus singletons, and within each plurality by the lowest rate compared to all other rates as relative risks ±95% CIs. Perinatal death rates can be reduced by more than 90% with attainment of birthweight and gestational age a within a plurality-specific ideal range.To determine cut-off point for discordant twins, and to clarify whether perinatal deaths are caused by discordancy or low birth weight itself, twin dataset was analized. Perinatal mortality rate was higher than that among discordancy less than 20%.Perinatal death of Japanese twins was significantly affected by both discordancy and low birth weight.

在日本，出生、死亡和死胎证明目前存储在磁带上的数据文件中。这些证书在市卫生局存档，并在日本厚生劳动省转为计算机档案。该数据库包含性别、出生体重、胎次、胎次、父母年龄等信息，多胎对按出生地、父母年龄、胎次、出生年月等进行识别，多胎双胞胎的出生体重明显大于非多胎双胞胎。本研究结果可用于日本多胎出生体重的评估，根据胎龄计算的中位出生身长以双胎最大，三胎次之，四胎最小，双胎的出生身长短于单胎，但其差异小于双胎与单胎之间的出生体重差异。多胎新生儿生长不对称，围产期死亡率按胎重和胎龄分类进行比较，双胎和三胎与单胎，每一多胎中最低发生率与所有其他发生率相比作为相对危险度± 95%CI。出生体重和胎龄a在多特异性的理想范围内，可使围产儿死亡率降低90%以上，为确定不一致双胞胎的截断点，明确围产儿死亡是由不一致还是低出生体重本身引起，对双胞胎数据集进行了分析。围生儿死亡率高于不和谐组，不和谐组围生儿死亡率高于低出生体重组，差异有统计学意义（P <0.05）。