Temporal and spatial aspects on divergence of the subfamily Munnae.

我们对主要来自欧亚大陆的17种旧大陆鼠属鼠的线粒体（细胞色素b，12S rRNA）和核（IRBP,RAG1）基因进行了测序。对新序列和已有序列的系统发育分析支持在家鼠中识别四个亚属（家鼠，Coelomys,Nannomys,Pyromys），但未确定的基部多切分。我们的数据进一步表明，小家鼠亚属包含三个不同的“种群”：1)小家鼠种群，也包括M.terncolor和M.fragilicauda（也可能是M.famulus）；2) a小家鼠种群，包括小家鼠和小家鼠；3)小家鼠种群，包括马其顿小家鼠、spicilegus和spretus小家鼠。欧亚小家鼠的物种多样性可能可以解释为范围扩展和迁移的几个阶段，以及群体内经历生物群落转变的倾向。家鼠的IRBP和RAG1分子钟将家鼠亚属的起源追溯到大约5-6亿年前，家鼠亚属的种群的起源大约在2-3亿年前。欧亚鼠的进化时间模式与欧亚温带鼠属的进化时间模式相似。

We sequenced mitochondrial (cytochrome b,12S rRNA) and nuclear (IRBP,RAG1) genes for 17 species of the Old World murine genus Mus, drawn primarily from Eurasia. Phylogenetic analysis of the newly and previously available sequences support recognition of four subgenera within Mus (Mus,Coelomys,Nannomys,Pyromys), with an unresolved basal polytomy. Our data further indicate that the subgenus Mus contains three distinct 'species groups' : 1) a Mus booduga Species Group, also including M.terncolor and M.fragilicauda (probably also M.famulus) ; 2) a Mus cervicolor Species Group, also including M.caroli and M.cookii ; and 3) a Mus musculus Species Group, also including M.macedonicus, M.spicilegus and M.spretus. Species diversity in Eurasian Mus is probably explicable in terms of several phases of range expansion and vicariance, and by a propensity within the group to undergo biotope transitions. IRBP and RAG1 molecular clocks for Mus date the origin of subgenera to around 5-6 mya and the origin of Species Groups within subgenus Mus to around 2-3 mya. The temporal pattern of evolution among Eurasian Mus is similar to that within the Eurasian temperate genus Apodemus.