Assssing evolutionary episodes of genetic hybridization in small mammals using the population haplotype structure analysis

在这项研究中,我们旨在开发一种新的方法来更好的理解空间和时间方面的辅助触点不同地理群体的两种截然不同的血统混杂,专注于复合信号沿着某些染色体部分,如10 kb、200 kb, 1 Mb,和5 Mb。在一个200 kb的部分,例如,我们确定在八个基因核苷酸序列区域(~ 500个基点)被分离在20 - 30 kb间隔和评估其单体型结构。这些方法使我们能够探测到不同时间尺度的二次接触事件，如几百年前和几十万年前。该方法有待进一步改进，旨在建立在分子系统地理学研究中充分利用重组事件相关遗传信息的途径。

In this study, we aimed to develop a new method to better understand spacial and temporal aspects for the secondary contact in which two distinct lineages of different geographic groups are mingled, focusing on recombination signals along a certain chromosome portion, such as 10 kb, 200 kb, 1 Mb, and 5 Mb. In a case of 200 kb segment, for example, we determined nucleotide sequences in eight gene region (~500 bp) being separated at 20-30 kb interval and assessed its haplotype structures. These methods allowed us to detect the secondary contact events of different time scales, such as several hundred years before present and several hundred thousand years ago. Further efforts would be needed to improve the method, aiming at establishment of ways to fully utilize the genetic information related to recombination events in molecular phylogeographic study.