Analysis of mechanisms for formation of pathogenic immune complexes and establishment of novel therapeutic approach in IgA nephropathy
Analysis of mechanisms for formation of pathogenic immune complexes and establishment of novel therapeutic approach in IgA nephropathy
批准号:
22790802
负责人:
SUZUKI Hitoshi
金额:
$2.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
IgA nephropathy(IgAN), the most common glomerulonephritis, is characterized by mesangial IgA1-containing immunodeposits. Aberrant IgA1 and anti-glycan IgG are produced by activation of TLR9 and several cytokines. Serum levels of aberrant IgA1, anti-glycan IgG, and IgG-IgA immune complexes may be useful biomarkers for judgment of indication of tonsillectomy and efficacy of therapy.
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IgA腎症の発症、扁桃病巣感染、粘膜免疫
IgA 肾病、扁桃体局灶性感染、粘膜免疫的发展
DOI:
--
发表时间:
2011
期刊:
IgA腎症診療ガイドQ & A進行性腎障害診療指針シリーズ
影响因子:
--
作者:
[鈴木仁, 富野康日己, 鈴木仁]
通讯作者:
鈴木仁
Evaluation of Serial Serum Levels of IgA-IgG Immune Complexes Prior To Diagnosis of IgA Nephropathy
IgA 肾病诊断前 IgA-IgG 免疫复合物连续血清水平的评估
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Olson SW, Suzuki H, et al]
通讯作者:
et al
Novel noninvasive biomarkers for disease activity of IgA nephropathy
IgA 肾病疾病活动性的新型非侵入性生物标志物
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Suzuki Y, Matsuzaki K, Suzuki H, et al]
通讯作者:
et al
Novel diagnostic approach for IgA nephropathy
IgA 肾病的新诊断方法
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Yanagawa H, Suzuki H, et al]
通讯作者:
et al
糖鎖異常IgA1
聚糖异常 IgA1
DOI:
--
发表时间:
2011
期刊:
IgA腎症診療マニュアル
影响因子:
--
作者:
[鈴木仁, 富野康日己]
通讯作者:
富野康日己
共 26 条
Understanding the evolutionary dynamics of hair color related genes of small mammals and development of phylogeographicl markers
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批准号:15K07177
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2015
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负责人:SUZUKI Hitoshi
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依托单位:
Investigation into novel splicing targets of Nucleophosmin
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批准号:24700974
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
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财政年份:2012
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负责人:SUZUKI Hitoshi
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依托单位:
Pathogenic role of galactose-deficient IgA1 contained immune complexes and tonsillar cells in IgA nephropathy
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批准号:24591213
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:SUZUKI Hitoshi
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依托单位:
Assssing evolutionary episodes of genetic hybridization in small mammals using the population haplotype structure analysis
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批准号:23570101
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
-
财政年份:2011
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负责人:SUZUKI Hitoshi
-
依托单位:
Evidences of a novel splicing mechanism in DMD gene
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批准号:22710192
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.5万
-
财政年份:2010
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负责人:SUZUKI Hitoshi
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依托单位:
Molecular phylogeny of species of Rattus and Mus and its use for biodiversity studies
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批准号:20570078
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2008
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负责人:SUZUKI Hitoshi
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依托单位:
Molecular phylogeny and gene evolution in Eurasian small mammals during the late Tertiary to the present
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批准号:19405010
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$3.41万
-
财政年份:2007
-
负责人:SUZUKI Hitoshi
-
依托单位:
Study on International Network of Production under the EU Enlargement
-
批准号:18530162
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.2万
-
财政年份:2006
-
负责人:SUZUKI Hitoshi
-
依托单位:
Molecular phylogeny of Rattus species and their temporal, spatial, and ecological modes of evolution
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批准号:16570071
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
-
财政年份:2004
-
负责人:SUZUKI Hitoshi
-
依托单位:
Molecular phylogenetic study on the movements of small mammals across the continents during the late Tertiary.
-
批准号:16405011
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$2.88万
-
财政年份:2004
-
负责人:SUZUKI Hitoshi
-
依托单位:
Study on Creation of National Economy under the Monetary Union and EU Company's Location of Industry
-
批准号:14530041
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.92万
-
财政年份:2002
-
负责人:SUZUKI Hitoshi
-
依托单位:
Temporal and spatial aspects on divergence of the subfamily Munnae.
-
批准号:14540638
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:2002
-
负责人:SUZUKI Hitoshi
-
依托单位:
Immuno-pathological studies in IgA nephropathy : The role of virus for etiological and progressive factors
-
批准号:13670823
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:2001
-
负责人:SUZUKI Hitoshi
-
依托单位:
Study of FDI to Central Eastern Europe and Hollowing out of EU industry
-
批准号:10630030
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.02万
-
财政年份:1998
-
负责人:SUZUKI Hitoshi
-
依托单位:
Immuno-pathological studies in IgA nephropathy : The role of virus for etiological and progressive factors
-
批准号:10670743
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:1998
-
负责人:SUZUKI Hitoshi
-
依托单位:
Genetic interaction between Russian and Japanese small mammals.
-
批准号:09041139
-
项目类别:Grant-in-Aid for Scientific Research (C).
-
资助金额:$1.92万
-
财政年份:1997
-
负责人:SUZUKI Hitoshi
-
依托单位:
Inttra-and interspecific genetic exchanges in Japanese small mammals through the Quaternary environmental fluctuations
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批准号:08640791
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1996
-
负责人:SUZUKI Hitoshi
-
依托单位:
Immuno-pathological studies in IgA nephropathy : The role of virus for etiological and progressive factors
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批准号:06670813
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1994
-
负责人:SUZUKI Hitoshi
-
依托单位:
Immuno-pathological studies in IgA nephropathy : The role of virus for etiological and progressive factors
-
批准号:03670502
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1991
-
负责人:SUZUKI Hitoshi
-
依托单位:
Immuno-pathological studies in IgA nephropathy : The role of virus for etiological and progressive factors
-
批准号:63570448
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1988
-
负责人:SUZUKI Hitoshi
-
依托单位:
海外基金