Risk evaluation and toxicity mechanism of air-borne particulate matter and its major chemical components
Risk evaluation and toxicity mechanism of air-borne particulate matter and its major chemical components
批准号:
17310039
负责人:
YAGI Takashi
金额:
$11.16万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2008
中文摘要
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英文摘要
堺市で採取した大気浮遊粒子の変異原性および内分泌撹乱性(ダイオキシン受容体およびエストロゲン受容体リガンド活性)を確認した。その主たる成分であるベンゾ(a)ピレン、1, 8-ジニトロピレン、3, 6-ジニトロベンゾ(e)ピレン、3-ニトロベンズアントロン、4-アミノビフェニルの突然変異誘発機構を分子・細胞生物学的方法で調べ、それらに共通した細胞周期特異的なDNA 損傷応答、および損傷に特異的なDNA ポリメラーゼの関与と突然変異誘発性を明らかにした。
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Structural identification of DNA adducts derived from 3-Nitrobenzanthrone, a potent carcinogen present in the atmosphere
源自 3-硝基苯并蒽酮(大气中存在的强效致癌物)的 DNA 加合物的结构鉴定
DOI:
--
发表时间:
2007
期刊:
Chem. Asian J 2
影响因子:
--
作者:
[Takamura-Enya, T., Kawanishi, M. Yagi, T.and Hisamatsu, Y.]
通讯作者:
Y.
神経系培養細胞PC12における酢酸鉛のタンパク質発現変動
培养神经系统细胞PC12中乙酸铅蛋白表达的变化
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[中山亜紀, 友松千晴, 谷修介, 森澤眞輔, 大川克也, 米田稔]
通讯作者:
米田稔
大気と微粒子の話
大气和颗粒物的故事
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[酒井哲(分担執筆, 第4章4.1), 皆巳幸也]
通讯作者:
皆巳幸也
Structural ldentification of DNA Adducts Derived from 3-Nitrobenzanthrone, a Potent Carcinogen Present in the Atmosphere
大气中存在的强效致癌物 3-硝基苯并蒽酮衍生的 DNA 加合物的结构鉴定
DOI:
--
发表时间:
2007
期刊:
Chemistry an Asian Journal 2
影响因子:
--
作者:
[Takamura-Enya, T., Kawanishi, M., Yagi, T. and Hisamatsu, Y.]
通讯作者:
Y.
A physiologically based pharmacokinetic model for endosulfan in the male Sprague-Dawley rats
雄性斯普拉格-道利大鼠体内硫丹的生理药代动力学模型
DOI:
--
发表时间:
2006
期刊:
Environ. Toxicol 21(5)
影响因子:
--
作者:
[Chan, M.P., Morisawa, S, Nakayama, A., Kawamoto, Y., Sugimoto, M., Yoneda, M.]
通讯作者:
M.
共 32 条
Involvement of Nrf / ARE signaling pathway in ischemia tolerance phenomenon
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批准号:26462154
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2014
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负责人:YAGI Takashi
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依托单位:
A study on mechanisms of delayed micronucleus induction using live-cell imaging methods
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批准号:24310047
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
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财政年份:2012
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负责人:YAGI Takashi
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依托单位:
Screening of epimutagens using DNA repair system
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批准号:24651063
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2012
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负责人:YAGI Takashi
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依托单位:
New Productivity Indexes and Capital Theory
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批准号:17530137
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.64万
-
财政年份:2005
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负责人:YAGI Takashi
-
依托单位:
Evaluation of influences of air-borne particulates by molecular and cellular biological methods
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批准号:14380257
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.47万
-
财政年份:2002
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负责人:YAGI Takashi
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依托单位:
Establishment of Cell Strains Deficient in Genes Related to Mutation Induction, and Analysis of Mutation Mechanisms Using the Cell Strains.
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批准号:12680542
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2000
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负责人:YAGI Takashi
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依托单位:
Phylogeny and evolution of Japanese papilionid butterflies inferred from mitochondrial DNA sequences
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批准号:09839014
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:1997
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负责人:YAGI Takashi
-
依托单位:
Analysis of mechanisms of DNA repair and UV-induced mutation by a cell-free system.
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批准号:07839005
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1995
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负责人:YAGI Takashi
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依托单位:
Qualitative difference in radiation-induced mutations by the difference in DNA repair mechanisms among cells.
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批准号:04680211
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.6万
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财政年份:1992
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负责人:YAGI Takashi
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依托单位:
Analysis of mutations induced in cells derived from DNA repair-deficient hereditary disease patients.
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批准号:02671046
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1990
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负责人:YAGI Takashi
-
依托单位:
海外基金