Development of new diagnostic markers and drug based on comprehensive search of gene and protein in hepatocellular carcinoma
Development of new diagnostic markers and drug based on comprehensive search of gene and protein in hepatocellular carcinoma
批准号:
18390366
负责人:
OKA Masaaki
金额:
$11.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2006
资助国家:
日本
项目状态:
已结题
起止时间:
2006 至 2008
中文摘要
点击翻译按钮获取中文摘要
英文摘要
肝癌の新規診断と創薬の研究を行った。新規診断では、カスタムチップおよび定量的PCR による肝切除後早期再発予測システムを開発した。タンパク診断では、肝癌の新たなマーカーとして3 種類(HSP70、PRX、Mn-SOD)の自己抗体を検出できた。創薬としては、ID2 遺伝子およびENO1 タンパクが標的になること、さらにはID2 発現がHDAC 阻害剤の分子マーカーとなることを発見した。
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Geographic bias-based resampling approach reveals a common pathway in early intrahepatic recurrence of hepatocellular carcinoma.
基于地理偏差的重采样方法揭示了肝细胞癌早期肝内复发的共同途径。
DOI:
--
发表时间:
2007
期刊:
Anticancer Research 27
影响因子:
--
作者:
[Yamashita K, Ougolkov A, Nakazato H, Ito K, Ohashi Y, Kitakata H, Yasumoto K, Omote K, Mai M, Takahashi Y, Minamoto T., Uchimura S.]
通讯作者:
Uchimura S.
Esophageal squamous cell carcinomas with distinct invasive depth show different gene expression profiles associated with lymph nodemetasstasis.
具有不同浸润深度的食管鳞状细胞癌表现出与淋巴结转移相关的不同基因表达谱。
DOI:
--
发表时间:
2006
期刊:
Int J Oncol. 28・5
影响因子:
--
作者:
[田辺稔(慶應義塾大学外科), 上田政和, 河地茂行, 篠田昌宏, 日比泰造, 小島正之, 半田寛, 丸山正太郎, 山本立真, 高野公徳, 北川雄光, 吉岡達也, Sato T.]
通讯作者:
Sato T.
解糖系モジュールと肝細胞癌(HCC)の進展
糖酵解模块与肝细胞癌(HCC)的发展
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Minamoto T, Yamashita K, Kawakami K., 飯塚徳男]
通讯作者:
飯塚徳男
肝癌細胞の早期肝内再発に対するリアルタイムRT-PCR を応用した予測システムの開発
开发肝癌细胞早期肝内复发实时RT-PCR预测系统
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[小西小百合, ら, 蘇村秀明]
通讯作者:
蘇村秀明
Supervised visualization of microarray date by statistical pattern recognition
通过统计模式识别对微阵列数据进行监督可视化
DOI:
--
发表时间:
2005
期刊:
影响因子:
--
作者:
[Utsunomiya, T., 他, Miyamato T.]
通讯作者:
Miyamato T.
共 45 条
Identification of the HSP70 peptide for the development of cancer immunetherapy
-
批准号:26670606
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2014
-
负责人:OKA Masaaki
-
依托单位:
Development of immune therapy which targets pancreatic cancer stem cells
-
批准号:24390317
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.65万
-
财政年份:2012
-
负责人:OKA Masaaki
-
依托单位:
Development and publication of Web page platform on ICT teaching materials of plant education for 4D observation and imaginary experience
-
批准号:24501088
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2012
-
负责人:OKA Masaaki
-
依托单位:
Development of new program for agricultural education by using the computer software Virtual Field System and the many movies recording plant growth
-
批准号:21500864
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2009
-
负责人:OKA Masaaki
-
依托单位:
Development of diagnostic system of early hepatocellular carcinoma by methylation of multiple genes
-
批准号:21390379
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.15万
-
财政年份:2009
-
负责人:OKA Masaaki
-
依托单位:
Development and release of the series of the software for agricultural education
-
批准号:19500718
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.0万
-
财政年份:2007
-
负责人:OKA Masaaki
-
依托单位:
Immunotherapy for prevention of postoperative recurrence in pancreatic cancer using cell therapy and vaccine therapy
-
批准号:15390397
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.28万
-
财政年份:2003
-
负责人:OKA Masaaki
-
依托单位:
Relation between nm23-H1 expression and effect of chemotherapy for hepatocellular carcinoma
-
批准号:12671230
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2000
-
负责人:OKA Masaaki
-
依托单位:
Immunotherapy using cytotoxic T cell and peptide vaccine for pancreatic cancer
-
批准号:12557104
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.19万
-
财政年份:2000
-
负责人:OKA Masaaki
-
依托单位:
Adoptive immunotherapy using MUC1 specific cytotoxic T lymphocytes for pancreatic cancer
-
批准号:08671445
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
-
财政年份:1996
-
负责人:OKA Masaaki
-
依托单位:
New Immunotherapy for hepatocellular carcinoma after hepatectomy
-
批准号:05671066
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1993
-
负责人:OKA Masaaki
-
依托单位:
New immunotherapy for prevention of liver metastasis from colorectal cancer after surgery.
-
批准号:02670579
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1990
-
负责人:OKA Masaaki
-
依托单位:
海外基金