QOL improvement through the pain control by the milk-derived lactoferrin in the animals

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Neoplastic or neurological diseases are in a tendency to increase in aged animals. Because a lot of cases that it is difficult for these disorders to completely heal are accompanied with chronically pain, it is failed to be remarkable as for the animal's QOL. In this project, we used lactoferrin which is safety and food origin, to depress chronic inflammation and pain such as the arthritis. Lactoferrin had suppressing effects on neural transmission of the chronic pain and sympathetic hyper activity in stressful condition. Finally, it is suggested that lactoferrin is one of the useful supplements to improve animal's QOL.