Development of injectable scaffolds including DNA/polycation complexes
Development of injectable scaffolds including DNA/polycation complexes
批准号:
19390505
负责人:
FUKUSHIMA Tadao
金额:
$11.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
The DNA/polycation complexes were prepared by reaction between salmon tests DNA and polycations (Chitosan, poly-L-arginine, poly-L-histidine, poly-L-lysine, and protamine) in order to investigated the potential of the complexes for injectable scaffolds. DNA/chitosan and DNA/protamine complexes were mobile paste. These complexes including carbonate apatite were also mobile paste, and created new bone in vivo test. It is expected that DNA/chitosan and DNA/protamine complexes will be useful as biomaterials for injectable scaffolds.
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海外基金