Genetic epidemiological research on drug resistant malaria which has originated and been spreading in Asian countries.

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In the malaria endemic Philippines, the level of genetic diversity of Plasmodium falciparum correlates with the local malaria endemicity. The Thai P.f.populations had been under strong chloroquine selective pressure but the Vietnamese population had not, and that the origin of chloroquine resistance in Vietnam might be different from Thailand. The genealogical origin of P. vivax populations in South Korea was from the two different populations in southern China. These findings confirm that population genetic analyses are a useful tool for epidemiology of malaria.