Study of neurite elongation mechanisms of early-late endosome transfer
Study of neurite elongation mechanisms of early-late endosome transfer
批准号:
19500338
负责人:
AOKI Shunsuke
金额:
$2.41万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
点击翻译按钮获取中文摘要
英文摘要
We studied on the intracellular mechanisms of neurite elongation controlled by early-late endosome transition modulated by Solo, Rho GTPase and class C VPS/HOPS molecules. We found that Rac is a major downstream signal regulator for neurite elongation induced by Solo and that VPS39 plays an important role in the cellular signal transduction. Moreover, we established a novel in vivo bioassay for neurite elongation/nerve regeneration by ligation of dissected rat facial nerve with silicon tube.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1093/hmg/ddn037
发表时间:
2008-05-15
期刊:
HUMAN MOLECULAR GENETICS
影响因子:
3.5
作者:
[Kabuta, Tomohiro, Setsuie, Rieko, Wada, Keiji]
通讯作者:
Wada, Keiji
DOI:
10.1111/j.1460-9568.2008.06026.x
发表时间:
2008-02-01
期刊:
EUROPEAN JOURNAL OF NEUROSCIENCE
影响因子:
3.4
作者:
[Sasaki, Ryo, Aoki, Shunsuke, Ogiuchi, Hideki]
通讯作者:
Ogiuchi, Hideki
DOI:
10.1016/j.neuint.2008.12.005
发表时间:
2009-05-01
期刊:
NEUROCHEMISTRY INTERNATIONAL
影响因子:
4.2
作者:
[Kimiwada, Tomomi, Sakurai, Mikako, Wada, Keiji]
通讯作者:
Wada, Keiji
DOI:
10.1111/j.1471-4159.2006.04339.x
发表时间:
2007-04-01
期刊:
JOURNAL OF NEUROCHEMISTRY
影响因子:
4.7
作者:
[Noda, Mami, Kariura, Yukihiro, Wada, Keiji]
通讯作者:
Wada, Keiji
UCH-Lファミリー分子群を標的としたin silicoドッキング・シミュレーションによる新規作用薬剤の同定
通过针对 UCH-L 家族分子的计算机对接模拟识别新型药物
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[柳澤比呂子, 豊田雅士, 元山純, 吉田瞳, 中野芳朗, 川野仁, 山元大輔, 三五一憲, 青木 俊介]
通讯作者:
青木 俊介
共 14 条
海外基金