Development and application of sensors selective to biologically active substances
Development and application of sensors selective to biologically active substances
批准号:
19590039
负责人:
KATSU Takashi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
We developed new sensors selective to caffeine and reactive oxygen species such as hydroxyl radical and superoxide anion. We utilized a commercially available oxygen electrode to detect reactive oxygen species. Applications of sensors were performed to determine the precise channel sizes of biologically active substances formed in cellular membranes and to elucidate the mechanism of photo-inactivated action of porphyrins on bacterial membranes.
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大腸菌外膜の透過性を亢進する物質の探索:アミジノ基を2個有する両親媒性物質
寻找增加大肠杆菌外膜通透性的物质:具有两个脒基的两亲性物质
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[武田紀彦, 宮田興子, 内藤猛章, 駒越圭子]
通讯作者:
駒越圭子
DOI:
10.2116/analsci.24.1551
发表时间:
2008-12-01
期刊:
ANALYTICAL SCIENCES
影响因子:
1.6
作者:
[Katsu, Takashi, Okada, Shiho, Nakao, Satoshi]
通讯作者:
Nakao, Satoshi
Oxygen electrode as a new t001 to evaluate hydroxyl radical-scavenging ability
氧电极作为新型t001评价羟自由基清除能力
DOI:
--
发表时间:
2008
期刊:
Sensors and Actuators B 134
影响因子:
--
作者:
[宮田興子, 河井小百合, 内藤猛章, Keiko Komagoe]
通讯作者:
Keiko Komagoe
ポルフィリンによる細菌の光不活性化:抗菌作用と膜電位低下との相関
卟啉对细菌的光灭活:抗菌作用与膜电位下降之间的相关性
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Takiyama, K., Eiji Kinoshita, Kinoshita-Kikuta, E., Fujioka, Y., Kubo, Y., and Koike, T., 宮本佳奈]
通讯作者:
宮本佳奈
A caffeine-sensitive membrane electrode : previous misleading report and present approach
咖啡因敏感膜电极:之前的误导性报告和目前的方法
DOI:
--
发表时间:
2008
期刊:
Analytica Chimica Ada 620
影响因子:
--
作者:
[宮田興子, 白井淳, 山田登美子, 金村米博, 内藤猛章, Takashi Katsu]
通讯作者:
Takashi Katsu
共 20 条
In situ monitoring of drug action using electrochemical sensors
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批准号:25460036
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2013
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负责人:KATSU Takashi
-
依托单位:
New development of studies on the interaction between cell membranes and drugs using sensors
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批准号:22590036
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2010
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负责人:KATSU Takashi
-
依托单位:
Development and application of high-performance ion-selective electrodes
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批准号:16590027
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2004
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负责人:KATSU Takashi
-
依托单位:
Development of drug electrodes with high sensitivity and selectivity
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批准号:10672019
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:1998
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负责人:KATSU Takashi
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依托单位:
Development of electrochemical sensors responding to biologically active substances
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批准号:08672477
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1996
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负责人:KATSU Takashi
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依托单位:
Development and application of ion-selective electrodes
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批准号:06672144
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1994
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负责人:KATSU Takashi
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依托单位:
Amphiphile-induced incorporation of a substance into cells
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批准号:03671026
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.28万
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财政年份:1991
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负责人:KATSU Takashi
-
依托单位:
Mechanism of Biological Membrane Damage Induced by Amphiphilic Drugs and Peptides
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批准号:01571178
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1989
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负责人:KATSU Takashi
-
依托单位:
Action mechanism of cationic drugs increasing the permeability of an outer membrane of Gram-negative bacteria
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批准号:62570967
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.28万
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财政年份:1987
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负责人:KATSU Takashi
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依托单位:
海外基金