A development of the custom array for diagnoses to predict a risk of the periodontal-disease

我们制作了牙周病相关病原菌的基因表达芯片，用于诊断牙周病的状态，并检验了其实用性。以牙周病原菌牙龈卟啉单胞菌的所有基因探针为靶标，构建在阵列上。通过寻找牙周病临床恶化细菌的候选基因，我们证实了高表达的基因依赖于临床状态。因此，候选人似乎将在未来的诊断中有所帮助。

We produced a gene expression array for periodontal disease-associated pathogens to diagnose the state of periodontal disease, and inspected the utility. All gene probes of Porphyromonas gingivalis well-known as periodontal pathogen were targeted, and were built on the array. As a result of searching the candidate genes of the bacteria deteriorating clinical condition of periodontal disease, we confirmed high-expressed genes depend on the clinical state. Thus, it seems that the candidates will be helpful in the diagnosis in a future.