Enhancement of bone healing during distraction osteogenesis
Enhancement of bone healing during distraction osteogenesis
批准号:
20390401
负责人:
YASUI Natsuo
金额:
$12.65万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Rabbit tibial lengthening was achieved to examine the effect of local infusion of the growth factors and bisphosphonate into the lengthened segment. When FGF-2 and bisphosphonate were infused simultaneously during consolidation phase, bone healing was dramatically enhanced. FGF-2 stimulated bone formation while bisphosphonate inhibited bone resorption. We believe this method is valid to shorten the treatment time of limb lengthening and is applicable in the clinical field as a new drug delivery system.
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DOI:
10.1136/ard.2008.104315
发表时间:
2010-02-01
期刊:
ANNALS OF THE RHEUMATIC DISEASES
影响因子:
27.4
作者:
[Nishimoto, K., Kochi, Y., Momohara, S.]
通讯作者:
Momohara, S.
Association study of TRAF1-C5 polymorphisms with susceptibility to the umatoid arthritis and systemic lupus erythematosus in Japanese.
TRAF1-C5 多态性与日本人类瘤样关节炎和系统性红斑狼疮易感性的关联研究。
DOI:
--
发表时间:
2010
期刊:
Ann Rheum Dis
影响因子:
27.4
作者:
[Nishimoto K, et al.]
通讯作者:
et al.
Enhanced bone healing by local infusion of FGF-2 and bisphosphonate during distraction osteogenesis
牵张成骨过程中局部输注 FGF-2 和双磷酸盐可增强骨愈合
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Yasui N, et al.]
通讯作者:
et al.
Circumferential periosteal stripping of femoral diaphysis of developing rat produces longitudinal overgrowth and cortical hypertrophy.
发育中的大鼠股骨骨干的周向骨膜剥离产生纵向过度生长和皮质肥大。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Takata S, et al.]
通讯作者:
et al.
骨格筋の特性が脚延長への適応に与える影響
骨骼肌特性对腿部延长适应的影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[杉安謙仁朗, 南野勝彦, 吉川秀樹, 名井陽, Saito A, 小笠原邦昭, 和田卓郎, 高橋光彦]
通讯作者:
高橋光彦
共 18 条
Musculo-skeletal regeneration during distracionosteogenesis
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批准号:18390418
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.87万
-
财政年份:2006
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负责人:YASUI Natsuo
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依托单位:
Modulation of Bone Remodeling during Distraction Osteogenesis
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批准号:16390441
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.28万
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财政年份:2004
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负责人:YASUI Natsuo
-
依托单位:
BONE REMODELING IN THE CALLUS FORMED DURING -DISTRACTION OSTEOGENESIS
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批准号:14370465
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.38万
-
财政年份:2002
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负责人:YASUI Natsuo
-
依托单位:
Effect of tension-stress on gene expression of one and cartilage cells. Molecular mechanism of distraction osteogenesis
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批准号:12671413
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.43万
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财政年份:2000
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负责人:YASUI Natsuo
-
依托单位:
Molecular mechanism of distraction osteogenesis : Effect of tension-stress on bone formation.
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批准号:10671360
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:1998
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负责人:YASUI Natsuo
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依托单位:
海外基金