Establishment of new pathological analysis by imaging mass spectrometry
Establishment of new pathological analysis by imaging mass spectrometry
批准号:
20790419
负责人:
ZAIMA Nobuhiro
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
生化方法,如染色,被广泛用于病理分析。这些方法对于病理分析是必不可少的。然而,它们也有一些缺点。例如,它们不能应用于非目标分析。建立新的病理方法对分析特发性疾病具有重要意义。本研究建立了一种新的病理分析方法,采用成像质谱法进行非靶向分析。
英文摘要
Biochemical approaches, such as staining, are widely used as pathological analysis. These methods are essential for pathological analysis. However, they have some disadvantages. For example, they cannot be applied to non-targeting analysis. Establishment of new pathological method is important to analyze idiopathic disease. In this study, new pathological analysis using imaging mass spectrometry for non-targeting analysis was established.
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Imaging of metabolites by MALDI mass spectrometry.
通过 MALDI 质谱法对代谢物进行成像。
DOI:
--
发表时间:
2009
期刊:
Journal of Oleo Science
影响因子:
1.5
作者:
[N. Zaima, T. Hayasaka, Naoko Goto, M. Setou]
通讯作者:
M. Setou
The abnormal accumulation of metabolites in neutral lipid storage myopathy caused by adipose triacylglycerol lipase mutation.
脂肪三酰甘油脂肪酶突变引起的中性脂质贮积性肌病代谢物异常积累。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Zaima, N., Sugiura, Y., Hirano, K., Ohkuma, A., Okahashi, S., Noguchi, S., Nishino, I., Ibi, T., Sahashi, K., Setou, M.]
通讯作者:
M.
Principal component analysis of direct matrix-assisted laser desorption/ionization mass spectrometric data related to metabolites of fatty liver.
与脂肪肝代谢物相关的直接基质辅助激光解吸/电离质谱数据的主成分分析。
DOI:
10.5650/jos.58.267
发表时间:
2009
期刊:
Journal of oleo science
影响因子:
1.5
作者:
[N. Zaima, Y. Matsuyama, M. Setou]
通讯作者:
M. Setou
The pathological analysis of neutral lipid storage myopathy caused by a dipose triacylglycerol lipase mutation.
双性三酰甘油脂肪酶突变所致中性脂质贮积性肌病的病理分析
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Zaima, N., Sugiura, Y., Hirano, K., Ohkuma, A., Okahashi, S., Noguchi, S., Nishino, I., Ibi, T., Sahashi, K., Setou, M., Nobuhiro Zaima]
通讯作者:
Nobuhiro Zaima
Analysis of Lipid Storage Myopathy (ETFDH mutant or PNPLA2 mutant) by Direct Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
通过直接基质辅助激光解吸/电离质谱法分析脂质沉积性肌病(ETFDH 突变体或 PNPLA2 突变体)
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Zaima, N., Sugiura, Y., Hirano, K., Ohkuma, A., Okahashi, S., Noguchi, S., Nishino, I., Ibi, T., Sahashi, K., Setou, M., Nobuhiro Zaima, Nobuhiro Zaima]
通讯作者:
Nobuhiro Zaima
Investigation of new evaluation approach of functional food factors using in situ metabolomics
-
批准号:25660109
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$1.91万
-
财政年份:2013
-
负责人:ZAIMA Nobuhiro
-
依托单位:
Studies on development of examination of pathological condition using mass spectrometry imaging
-
批准号:25713024
-
项目类别:Grant-in-Aid for Young Scientists (A)
-
资助金额:$11.56万
-
财政年份:2013
-
负责人:ZAIMA Nobuhiro
-
依托单位:
Enhancement of utility of imaging mass spectrometry in pathophysiological examination
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批准号:22590522
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2010
-
负责人:ZAIMA Nobuhiro
-
依托单位:
海外基金