Identification of genetic markers for rhabdomyolysis indused by drug and the establishment of gene diagnosis

药物相关性横纹肌溶解症可能由遗传背景引起。我们分析了潜在的横纹肌溶解症的易感基因在尸检的药物中毒，如甲基苯丙胺的情况下。但本研究中观察到的基因突变与横纹肌溶解症之间无明显关系。需要更多的横纹肌溶解症尸检病例，对其他横纹肌溶解症易感基因的研究有助于明确横纹肌溶解症与遗传背景之间的关系。

There is a possibility that rhabdomyolysis related to drug can be caused by genetic background. We analyzed potential rhabdomyolysis-susceptibility genes in autopsy cases of drug poisoning such as methamphetamine. But there was no obvious relationship between the genetic mutations observed in this study and rhabdomyolysis. A lot more autopsy cases of rhabdomyolysis were required and investigation of other rhabdomyolysis-susceptibility genes helps to clear association between rhabdomyolysis and genetic background.