An approach to the diagnosis of sudden cardiac death : Investigation of a detection method for mutations in genes associated with inherited lethal cardiac arrhythmias

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In forensic autopsy cases suspected of sudden cardiac death, where autopsy findings and pathological examination revealed no signs of fatal disease, we searched for mutations in genes associated with inherited lethal cardiac arrhythmias. One mutation was found and it was suggested that this mutation was associated with sudden cardiac death. In forensic autopsy cases suspected of arrhythmogenic right ventricular cardiomyopathy(ARVC), we searched for mutations in genes associated with ARVC and some mutations were found. Genetic analysis is scientifically helpful in the diagnosis of sudden cardiac death in forensic autopsy cases.