The relationship of MMPs and growth factors in the invasion mechanism of adenoid cystic carcinoma
The relationship of MMPs and growth factors in the invasion mechanism of adenoid cystic carcinoma
批准号:
20791561
负责人:
TANAKA Noriaki
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
Adenoid cystic carcinoma is a malignant salivary gland tumor characterized by perineural and perivascular invasion. In this study, we found that MMP9 and MMP14 were associated with the invasion mechanism of adenoid cystic carcinoma. In addition, the expression of VEGF was found in the adenoid cystic carcinoma cells, and it was suggested that VEGF induced angiogenesis at peritumoral stroma. Furthermore, it might be thought that semaphorins, which were known as the neuron guidance factor, were associated with the invasion mechanism of adenoid cystic carcinoma.
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会议论文
Relations among expression of CXCR4, histological patterns, and metastatic potential in adenoid cystic carcinoma of head and neck
头颈部腺样囊性癌CXCR4表达与组织学形态及转移潜能的关系
DOI:
--
发表时间:
2008
期刊:
Int. J Oncol. 33
影响因子:
--
作者:
[Zushi Y, Noguchi K, Hashitani S, Sakurai K, Segawa E, Takaoka K, Toyohara Y, Tanaka N, Kishimoto H, Urade M]
通讯作者:
Urade M
histological patterns, and metastatic potential in adenoid cystic carcinoma of head and neck
头颈部腺样囊性癌的组织学模式和转移潜力
DOI:
--
发表时间:
2008
期刊:
CXCR4 vol.33
影响因子:
--
作者:
[Zushi Y, Noguchi K, Hashitani S, Sakurai K, Segawa E, Takaoka K, Toyohara Y, Tanaka N, Kishimoto H, Urade M]
通讯作者:
Urade M
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Zushi Y, Noguchi K, Hashitani S, Sakurai K, Segawa E, Takaoka K, Toyohara Y, Tanaka N, Kishimoto H, Urade M, Tanaka N]
通讯作者:
Tanaka N
総合ビタミン製剤の連続投与が高度腎機能障害患者に及ぼす影響の解明
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批准号:19H00350
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项目类别:Grant-in-Aid for Encouragement of Scientists
-
资助金额:$0.35万
-
财政年份:2019
-
负责人:TANAKA Noriaki
-
依托单位:
Contribution of chemokines and growth factors for the cervical lymph node metastasis in oral squamous cell carcinoma
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批准号:24792206
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
-
财政年份:2012
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负责人:TANAKA Noriaki
-
依托单位:
Hepatic differentiation of human embryonic stem cells and its application to the development of a bioartificial liver system
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批准号:19390334
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.15万
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财政年份:2007
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负责人:TANAKA Noriaki
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依托单位:
Elucidation, of the interacting mechanism between epigenetic and genetic alterations in gastrointestinal cancers and of the possible application to the clinic
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批准号:17390368
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.92万
-
财政年份:2005
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负责人:TANAKA Noriaki
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依托单位:
Development of Regenerative Medicine Using Reversibly Proliferating Human Bone Marrow Mesenchymal Stem Cells
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批准号:15390378
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.41万
-
财政年份:2003
-
负责人:TANAKA Noriaki
-
依托单位:
Bioartificial liver development using reversibly immortalized human liver cell lines.
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批准号:13470236
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.56万
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财政年份:2001
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负责人:TANAKA Noriaki
-
依托单位:
Cell cycle transactivation factor E2F-4 is associate with the ganstrointestinal carcinogenesis and/or acquisition of chemoresistance
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批准号:11671237
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1999
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负责人:TANAKA Noriaki
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依托单位:
Role of ornithine decarboxylase (ODC) as a oncogene in colorectal tumorigenesis
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批准号:08671368
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.45万
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财政年份:1996
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负责人:TANAKA Noriaki
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依托单位:
THE IMMUNOLOGICAL HYPORESPONSIVENESS AND DONOR CELL PERSISTENCE IN HOST LIVER AFER PORTAL VENOUS INNOCULATION
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批准号:06671205
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.09万
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财政年份:1994
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负责人:TANAKA Noriaki
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依托单位:
Studies on the functions of the actirated lymphocytes after partial hepatectomy
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批准号:60480293
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.24万
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财政年份:1985
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负责人:TANAKA Noriaki
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依托单位:
海外基金