Australian Sea Anemone Venoms: Bioprospecting & Evolution

澳大利亚海葵是一种非常有前景的多肽和蛋白质来源，具有潜在的治疗和诊断应用。该项目旨在通过对澳大利亚水域的若干种海葵进行转录分析，并通过质谱学鉴定其毒液中的多肽和蛋白质，来评估这一潜力。它还将证明转录组学在海葵分类中的价值。此外，该项目将根据来自特定组织来源的线囊功能，评估物种内和物种之间的毒素多样性，并提供对澳大利亚猕猴桃毒液进化的更清楚的了解。

Australian sea anemones are a highly promising and largely unexplored source of peptides and proteins with potential therapeutic and diagnostic applications. This project aims to evaluate this potential by undertaking transcriptomic analyses of a number species of anemones from Australian waters and identifying peptides and proteins in their venoms by mass spectrometry. It will also demonstrate the value of transcriptomics in informing taxonomic classification of anemones. In addition this project will assess toxin diversity within and between species based on nematocyst function from specific tissue sources and provide a clearer understanding of the evolution of venoms in Australian Actiniaria.