Transcriptional gene regulation in the sensory nerve during chronic pain status.
Transcriptional gene regulation in the sensory nerve during chronic pain status.
批准号:
20591841
负责人:
AMAYA Fumimasa
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Expression of NF-IL6 and HMGB-1 was increased in the DRG in animal model of chronic pain. Inhibition of each of NF-IL6 or HMGB-1 alleviated pain hypersensitivity in chronic pain models suggesting that they are crucial for the development of chronic pain.
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DOI:
--
发表时间:
2009
期刊:
Canadian journal of Anaesthesia 56
影响因子:
--
作者:
[Mizukoshi K, Shibasaki M, Amaya F, et al.]
通讯作者:
et al.
DOI:
10.1523/jneurosci.5349-07.2008
发表时间:
2008-04-01
期刊:
JOURNAL OF NEUROSCIENCE
影响因子:
5.3
作者:
[Kohno, Tatsuro, Wang, Haibin, Woolf, Clifford J.]
通讯作者:
Woolf, Clifford J.
DOI:
10.1523/jneurosci.3795-08.2008
发表时间:
2008-12-24
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
[Binshtok AM, Wang H, Zimmermann K, Amaya F, Vardeh D, Shi L, Brenner GJ, Ji RR, Bean BP, Woolf CJ, Samad TA]
通讯作者:
Samad TA
DOI:
10.1016/j.pain.2010.03.023
发表时间:
2010-06-01
期刊:
PAIN
影响因子:
7.4
作者:
[Shibasaki, Masayuki, Sasaki, Mika, Amaya, Fumimasa]
通讯作者:
Amaya, Fumimasa
Nociceptors are interleukin-lbeta sensors
伤害感受器是白细胞介素-Lβ传感器
DOI:
--
发表时间:
2008
期刊:
Journal of Neuroscience 28
影响因子:
--
作者:
[Binshtok AM, Wang H, Zimmermann K, Amaya F, et al]
通讯作者:
et al
共 10 条
Analysis of pain hypersensitivity due to the mTOR mediated proteome alteration in the primary afferent neurons.
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批准号:23592306
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2011
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负责人:AMAYA Fumimasa
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依托单位:
海外基金