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Transcriptional gene regulation in the sensory nerve during chronic pain status.

Transcriptional gene regulation in the sensory nerve during chronic pain status.
慢性疼痛状态期间感觉神经的转录基因调节。
批准号:
20591841
负责人:
AMAYA Fumimasa
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
Expression of NF-IL6 and HMGB-1 was increased in the DRG in animal model of chronic pain. Inhibition of each of NF-IL6 or HMGB-1 alleviated pain hypersensitivity in chronic pain models suggesting that they are crucial for the development of chronic pain.
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DOI: --
发表时间: 2009
期刊: Canadian journal of Anaesthesia 56
影响因子: --
作者: [Mizukoshi K, Shibasaki M, Amaya F, et al.]
通讯作者: et al.
DOI: 10.1523/jneurosci.5349-07.2008
发表时间: 2008-04-01
期刊: JOURNAL OF NEUROSCIENCE
影响因子: 5.3
作者: [Kohno, Tatsuro, Wang, Haibin, Woolf, Clifford J.]
通讯作者: Woolf, Clifford J.
DOI: 10.1523/jneurosci.3795-08.2008
发表时间: 2008-12-24
期刊: The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子: --
作者: [Binshtok AM, Wang H, Zimmermann K, Amaya F, Vardeh D, Shi L, Brenner GJ, Ji RR, Bean BP, Woolf CJ, Samad TA]
通讯作者: Samad TA
DOI: 10.1016/j.pain.2010.03.023
发表时间: 2010-06-01
期刊: PAIN
影响因子: 7.4
作者: [Shibasaki, Masayuki, Sasaki, Mika, Amaya, Fumimasa]
通讯作者: Amaya, Fumimasa
10
    Analysis of pain hypersensitivity due to the mTOR mediated proteome alteration in the primary afferent neurons.
    • 批准号:
      23592306
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.33万
    • 财政年份:
      2011
    • 负责人:
      AMAYA Fumimasa
    • 依托单位:
    海外基金