Investigation of effect of soluble factors from adipose tissue on periodontitis, and development of prophylactic approach with these regulation
Investigation of effect of soluble factors from adipose tissue on periodontitis, and development of prophylactic approach with these regulation
批准号:
20592457
负责人:
AKIFUSA Sumio
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
关键词:
中文摘要
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英文摘要
We examined the effect of adiponectin, one of adipokine derived from mature adipocyte, on activity of macrophage, and found that administration of adiponectin reduced the lipopolysaccharide-induced inflammatory response. On the other hand, stimulation with adiponectin alone induced cytokine secretion, generation of reactive oxygen species and nitric oxide, followed by apoptotic cell death, in macrophage.
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DOI:
--
发表时间:
2010
期刊:
81(8)
影响因子:
--
作者:
[Shimazaki Y, Egami Y, Matsubara T, Koike G, Akifusa S, Jingu S, Yamashita Y.]
通讯作者:
Yamashita Y.
DOI:
10.1002/jcb.22745
发表时间:
2010-10-15
期刊:
JOURNAL OF CELLULAR BIOCHEMISTRY
影响因子:
4
作者:
[Akifusa, Sumio, Kamio, Noriaki, Yamashita, Yoshihisa]
通讯作者:
Yamashita, Yoshihisa
Relationship between chewing ability and high-level functional capacity in an 80-year-old population in Japan
日本80岁老年人咀嚼能力与高级功能能力的关系
DOI:
--
发表时间:
2008
期刊:
Gerodontology 25
影响因子:
--
作者:
[Takata Y, Ansai T, Soh I, Akifusa S, Sonoki K, Fujisawa K, Yoshida A, Kagiyama S, Hamasaki T, Nakamichi I, Awano S, Torisu T, Takehara T]
通讯作者:
Takehara T
DOI:
10.1111/j.1574-695x.2009.00573.x
发表时间:
2009-08-01
期刊:
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
影响因子:
--
作者:
[Kamio, Noriaki, Akifusa, Sumio, Yamashita, Yoshihisa]
通讯作者:
Yamashita, Yoshihisa
DOI:
10.3109/10715760903348328
发表时间:
2010-02-01
期刊:
FREE RADICAL RESEARCH
影响因子:
3.3
作者:
[Fujimoto, Akie, Akifusa, Sumio, Yamashita, Yoshihisa]
通讯作者:
Yamashita, Yoshihisa
共 21 条
The role of novel gasotransmitter hydrogen sulfide on inflammatory response in oral area
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批准号:24659937
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2012
-
负责人:AKIFUSA Sumio
-
依托单位:
Effect of senescent adipose tissue on periodontal disease states
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批准号:23390482
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.98万
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财政年份:2011
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负责人:AKIFUSA Sumio
-
依托单位:
The development for disrase model with periodontitis induced by Cytolethal Distending lbxin derived periodontal pathogens, and application of the model to periodontitis prevention
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批准号:18592285
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.32万
-
财政年份:2006
-
负责人:AKIFUSA Sumio
-
依托单位:
海外基金