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Investigation of effect of soluble factors from adipose tissue on periodontitis, and development of prophylactic approach with these regulation

Investigation of effect of soluble factors from adipose tissue on periodontitis, and development of prophylactic approach with these regulation
研究脂肪组织可溶性因子对牙周炎的影响,并开发利用这些调节的预防方法
批准号:
20592457
负责人:
AKIFUSA Sumio
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
We examined the effect of adiponectin, one of adipokine derived from mature adipocyte, on activity of macrophage, and found that administration of adiponectin reduced the lipopolysaccharide-induced inflammatory response. On the other hand, stimulation with adiponectin alone induced cytokine secretion, generation of reactive oxygen species and nitric oxide, followed by apoptotic cell death, in macrophage.
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DOI: --
发表时间: 2010
期刊: 81(8)
影响因子: --
作者: [Shimazaki Y, Egami Y, Matsubara T, Koike G, Akifusa S, Jingu S, Yamashita Y.]
通讯作者: Yamashita Y.
DOI: 10.1002/jcb.22745
发表时间: 2010-10-15
期刊: JOURNAL OF CELLULAR BIOCHEMISTRY
影响因子: 4
作者: [Akifusa, Sumio, Kamio, Noriaki, Yamashita, Yoshihisa]
通讯作者: Yamashita, Yoshihisa
DOI: --
发表时间: 2008
期刊: Gerodontology 25
影响因子: --
作者: [Takata Y, Ansai T, Soh I, Akifusa S, Sonoki K, Fujisawa K, Yoshida A, Kagiyama S, Hamasaki T, Nakamichi I, Awano S, Torisu T, Takehara T]
通讯作者: Takehara T
DOI: 10.1111/j.1574-695x.2009.00573.x
发表时间: 2009-08-01
期刊: FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
影响因子: --
作者: [Kamio, Noriaki, Akifusa, Sumio, Yamashita, Yoshihisa]
通讯作者: Yamashita, Yoshihisa
21
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    • 批准号:
      24659937
    • 项目类别:
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    • 资助金额:
      $2.41万
    • 财政年份:
      2012
    • 负责人:
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    • 依托单位:
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    • 批准号:
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    • 项目类别:
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    • 资助金额:
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    • 财政年份:
      2011
    • 负责人:
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    • 依托单位:
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    海外基金