Development of Highly Efficient Organocatalysts for Aerobic Oxidation Based on the Construction of Functionnalized Reaction Site around Flavin Molecules

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Construction of functionalized reaction site around the organocatalysts of flavin molecules is an attractive and convenient method to develop environmentaly benign highly efficient organocatalysts for aerobic oxidation. We have developed supramolecular flavin catalysts, which include dendronized flavin catalysts and flavin-functionalized gold nanoparticle catalysts. These flavin catalysts have proven to have high catalytic activity and substrate specificity based on the reaction sites constructed around the flavin molecules.