Gene-specific transcriptional regulation by heat shock factor
Gene-specific transcriptional regulation by heat shock factor
批准号:
21570181
负责人:
SAKURAI Hiroshi
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
HSF(heat shock factor) trimer, an evolutionarily conserved heat-responsive regulator, binds to heat shock element(HSE) and regulates expression of target genes. Continuous HSEs consist of contiguous inverted repeats of the nGAAn sequence, and discontinuous HSEs contain gaps in the array of the unit. This study shows that HSFs of various organisms, including human, bind discontinuous HSEs, as well as continuous HSEs. Furthermore, modulation of the trimer formation is important for the HSE specificity of HSFs.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1016/j.bbadis.2010.06.001
发表时间:
2010-09-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
影响因子:
6.2
作者:
[Enoki, Yasuaki, Mukoda, Yuka, Sakurai, Hiroshi]
通讯作者:
Sakurai, Hiroshi
さまざまな生物の熱ショック転写因子の機能解析
各种生物体热激转录因子的功能分析
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[榎康明, ら]
通讯作者:
ら
Mutational analysis of human heat-shock transcription factor 1 reveals a regulatory role for oligomerization in DNA-binding specificity.
人类热休克转录因子 1 的突变分析揭示了寡聚化在 DNA 结合特异性中的调节作用。
DOI:
--
发表时间:
2009
期刊:
Biochemical Journal
影响因子:
4.1
作者:
[Yukiko Takemori, Yasuaki Enoki, N. Yamamoto, Y. Fukai, K. Adachi, H. Sakurai]
通讯作者:
H. Sakurai
Measuring symmetry of wavefunctions at an interface in a magnetic tunneling junction
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批准号:21560322
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
-
财政年份:2009
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负责人:SAKURAI Hiroshi
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依托单位:
Recognition of diverse nucleotide sequences by heat shock transcription factors of various organisms
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批准号:19570164
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
-
财政年份:2007
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负责人:SAKURAI Hiroshi
-
依托单位:
Phosphorylation of heat shock transcription factor in the stress response
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批准号:16570142
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:SAKURAI Hiroshi
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依托单位:
Social system and self-organization
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批准号:14510228
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.96万
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财政年份:2002
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负责人:SAKURAI Hiroshi
-
依托单位:
Interaction between heat shock transcription factor and transcription initiation complex.
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批准号:13680760
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2001
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负责人:SAKURAI Hiroshi
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依托单位:
海外基金