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Molecular mechanism for the interaction between estrogen receptor and G protein-coupled receptor

Molecular mechanism for the interaction between estrogen receptor and G protein-coupled receptor
雌激素受体与G蛋白偶联受体相互作用的分子机制
批准号:
21590254
负责人:
ARITA Jun
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
It remains unknown how the interaction by G protein-coupled receptor is involved in the functional regulation of estrogen receptor. We showed that hypothalamic dopamine inhibited transcriptional activation of estrogen receptor through G protein-coupled dopamine receptor in pituitary lactotrophs in culture. The results suggest a novel mechanism of the interaction between nuclear receptors and cell membrane receptors.
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DOI: 10.1507/endocrj.k11e-104
发表时间: 2011-09-01
期刊: ENDOCRINE JOURNAL
影响因子: 2
作者: [Iguchi, Hironobu, Mitsui, Tetsuo, Arita, Jun]
通讯作者: Arita, Jun
Absence of ligand-independent transcriptional activation of the estrogen receptor via the estrogen response element in pituitary lactotrophs in primary culture
原代培养的垂体催乳素中不存在通过雌激素反应元件对雌激素受体进行配体依赖性转录激活
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Maho Ishida]
通讯作者: Maho Ishida
The cAMP response element-binding protein in the bed nucleus of the s tria terminalis modulates the formalin-induced pain behavior in the female rat
终丝床核中的 cAMP 反应元件结合蛋白调节雌性大鼠福尔马林诱导的疼痛行为
DOI: --
发表时间: 2009
期刊: European Journal of Neuroscience Vol.30
影响因子: --
作者: [Takamura M, Koga K, Osuga Y, Takemura Y, Hamasaki K, Hirota Y, Yoshino O, Taketani Y., Maho Ishida, Maho Ishida, Hiroko Hagiwara]
通讯作者: Hiroko Hagiwara
Fetal exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin(TCDD) induces expression of the chemokine genes Cxcl4 and Cxcl7 in the perinatal mouse brain
胎儿暴露于 2,3,7,8-四氯二苯并-对二恶英 (TCDD) 会诱导围产期小鼠脑中趋化因子基因 Cxcl4 和 Cxcl7 的表达
DOI: --
发表时间: 2011
期刊: Journal of Applied Toxicology
影响因子: 3.3
作者: [Mitsui, T., Taniguchi, N., Kawasaki, N., Kagami, Y., Arita, J.]
通讯作者: J.
10
    Identification of the gene involved in the anti-proliferative action of estrogen
    • 批准号:
      24590297
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.41万
    • 财政年份:
      2012
    • 负责人:
      ARITA Jun
    • 依托单位:
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      19590224
    • 项目类别:
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    • 资助金额:
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    • 财政年份:
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    • 负责人:
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    • 依托单位:
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    • 批准号:
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    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.24万
    • 财政年份:
      2005
    • 负责人:
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    • 依托单位:
    Identification of estrogen-responsive cells involved in cell proliferation in response to estrogen
    • 批准号:
      15590206
    • 项目类别:
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    • 资助金额:
      $2.24万
    • 财政年份:
      2003
    • 负责人:
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    • 依托单位:
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