Inhibition of P. gingivalis infection by the SLPI from gingival epithelial cells
Inhibition of P. gingivalis infection by the SLPI from gingival epithelial cells
批准号:
21592340
负责人:
KIMURA Shigenobu
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
The results indicated that gingival epithelial cells could be a substantial producer of secretory leukocyte protease inhibitor(SLPI) that functions inhibitory to the pathogenic Porphyromonas gingivalis protease in gingival crevices. It was also suggested that the SLPI production could increase in response to P. gingivalis through the stimulation with its pathogenic constituents.
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DOI:
10.1111/j.1600-0528.2009.00472.x
发表时间:
2009-06-01
期刊:
COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY
影响因子:
2.3
作者:
[Kishi, M., Abe, A., Yonemitsu, M.]
通讯作者:
Yonemitsu, M.
Auto-catalytic propeptide processing facilitates the final hetero-catalytic maturation of glutamyl endopeptidase GluV8
自催化前肽加工促进谷氨酰内肽酶 GluV8 最终异质催化成熟
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Ohara-Nemoto, Y., Rouf, S.M.A., Shimoyama, Y., Kimura, S., Ono, T. and Nemoto, T.K]
通讯作者:
T.K
Gene expression analyses of human macrophage phagocytizing sub-μ titanium particles by allergy DNA chip(Genopal^<TM>)
过敏DNA芯片(Genopal^<TM>)分析人巨噬细胞吞噬亚微米钛颗粒的基因表达
DOI:
--
发表时间:
2009
期刊:
Bio-mcd. Mater. Eng. 19(印刷中)
影响因子:
--
作者:
[Taira, M., Nezu, T., Sasaki, M., Kimura, S., Kagiya, T., Harada, H., Narushima T., Araki, Y.]
通讯作者:
Y.
Porphyromonas gingivalis DPP11の酵素活性とAsp/Glu特異性を規定するArg670
Arg670 定义了牙龈卟啉单胞菌 DPP11 的酶活性和 Asp/Glu 特异性
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[根本孝幸, 小野俊雄, 下山佑, 木村重信, 根本優子]
通讯作者:
根本優子
Prediction of colonization of periodontopathogens in plaque by VSC measurement.
通过 VSC 测量预测牙菌斑中牙周病原体的定植。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kishi, M., Ohara-Nemoto, Y., Kimura, S., Aizawa, F., Kishi, K., Takahashi, M., Yonemitsu, M.]
通讯作者:
M.
共 29 条
Infection control with SLPI via the inhibitory effect on the proteases of Porphyromonas gingivalis
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批准号:24592775
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.41万
-
财政年份:2012
-
负责人:KIMURA Shigenobu
-
依托单位:
Improvement and development of novel photosynthetic microorganisms which degradate aromatic pollutants in oligotrophic environment
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批准号:21241019
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$5.49万
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财政年份:2009
-
负责人:KIMURA Shigenobu
-
依托单位:
Identification of phosphorylated proteins in murine B cells in relation to the LPS-induced proliferative response
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批准号:19592129
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
-
负责人:KIMURA Shigenobu
-
依托单位:
Creation of novel photosynthetic microorganism for degradation of PCB in oligotrophic environment
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批准号:18310050
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.67万
-
财政年份:2006
-
负责人:KIMURA Shigenobu
-
依托单位:
CD14-dependent and independent pathways in B cells activation after stimulation with lipopolysaccharides from periodontopathic bacteria
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批准号:12470387
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.28万
-
财政年份:2000
-
负责人:KIMURA Shigenobu
-
依托单位:
Signal transduction mechanism by which lipopolysaccharides from various periodontopathic bacteria induce murine B lymphocyte activation
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批准号:09671851
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.98万
-
财政年份:1997
-
负责人:KIMURA Shigenobu
-
依托单位:
Phenotypic analysis of CD4^+CD45RA^+T cells in the inflamed gingiva of the patients with adult periodontitis
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批准号:05454526
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.42万
-
财政年份:1993
-
负责人:KIMURA Shigenobu
-
依托单位:
海外基金