Export of RNA-protein complex and oncogenesis
Export of RNA-protein complex and oncogenesis
批准号:
21592383
负责人:
ISHIKAWA Makoto
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In this study, we examined whether RNA binding proteins such as pp32 and HuR have oncogenic activity. AU-rich element(ARE) containing mRNA and HuR were exported to the cytoplasm of oral cancer cells. Although pp32 has potential to degrade HuR in the cytoplasm of cells, pp32r1 failed to do it. These results indicate that pp32r1 inhibits the degradation of HuR to stabilize ARE-mRNA and to transform cells
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
HuRタンパクの核外輸送と口腔がんとの関連
HuR蛋白核输出与口腔癌的关系
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[格口渉, 他, 黒嶋雄志, 黒嶋雄志]
通讯作者:
黒嶋雄志
HuR keeps an angiogenic switch on by stabilizing mRNA of VEGF and COX-2 in tumor endothelium
HuR 通过稳定肿瘤内皮中 VEGF 和 COX-2 的 mRNA 来保持血管生成开关开启
DOI:
--
发表时间:
2011
期刊:
Br J Cancer
影响因子:
--
作者:
[Kurosu T, Ohga N, Hida Y, Maishi N, Akiyama K, Kakuguchi W, Kuroshima T, Kondo M., Akino T., Totsuka Y., Shindoh M,Higashino F and Hida K]
通讯作者:
Shindoh M,Higashino F and Hida K
ARE-mRNAを安定化させることは細胞のがん化に寄与する
稳定 ARE-mRNA 有助于细胞癌变
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Hiroyuki Watanabe, Ryuzo Yanagimachi, Hiroyuki Taten, Kawamto T., 黒嶋雄志]
通讯作者:
黒嶋雄志
RNA結合タンパクHuRのノックダウンが口腔がんに及ぼす影響
RNA结合蛋白HuR敲低对口腔癌的影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[柴田哲男, 則竹瞬, Andrej Matsnev, 柴田哲男, Wataru Kakuguchi, 則竹瞬, Wataru Kakuguchi, 則竹瞬, Wataru Kakuguchi, 則竹瞬, Wataru Kakuguchi, 則竹瞬, 格口渉, 則竹瞬, Wataru Kakuguchi, 則竹瞬, 格口渉]
通讯作者:
格口渉
The phenotype of tumor lymphatic vessels could be a prognostic factor in human tongue squamous cell carcinoma
肿瘤淋巴管的表型可能是人舌鳞状细胞癌的预后因素
DOI:
--
发表时间:
2011
期刊:
Oncol Lett.
影响因子:
--
作者:
[Nitta Y, Hida K, Kitamura T, Higashino F, Fukushima K, Shindoh M]
通讯作者:
Shindoh M
共 27 条
Neuroprotection by enhancement of glutamate uptake against pressure-induced injury in a rat glaucoma model
-
批准号:24592666
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.41万
-
财政年份:2012
-
负责人:ISHIKAWA Makoto
-
依托单位:
Basic research on the youth social relationship cognition in network
-
批准号:23601004
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.25万
-
财政年份:2011
-
负责人:ISHIKAWA Makoto
-
依托单位:
Development of learning model about "efficiency" and "fairness" from the viewpoint of fair trade
-
批准号:23531189
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.16万
-
财政年份:2011
-
负责人:ISHIKAWA Makoto
-
依托单位:
Nationalist China's vision of returning to mainland China and formation of the relation between Nationalist China and U. S in the cold war era
-
批准号:22730147
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$1.58万
-
财政年份:2010
-
负责人:ISHIKAWA Makoto
-
依托单位:
Development of the learning model about the global capitalism economic system from the viewpoint of fair trade
-
批准号:20530819
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2008
-
负责人:ISHIKAWA Makoto
-
依托单位:
Using museum intellectual property to construct appreciation learning systems with a view to lifelong learning
-
批准号:20530818
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2008
-
负责人:ISHIKAWA Makoto
-
依托单位:
Fundamental research of kansei information for better text message communication
-
批准号:19700237
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$1.64万
-
财政年份:2007
-
负责人:ISHIKAWA Makoto
-
依托单位:
Roles of p53 family proteins on the risk-factor of recurrence in oral squamous cell carcinomas.
-
批准号:19592279
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.66万
-
财政年份:2007
-
负责人:ISHIKAWA Makoto
-
依托单位:
Roles of Pim-1 oncogene in oral squamous cell carcinoma.
-
批准号:17592059
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2005
-
负责人:ISHIKAWA Makoto
-
依托单位:
Building the Practical Programs for Art Appreciation in Lifelong Education through Collaborations between Schools and Art Museums.
-
批准号:15530585
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.05万
-
财政年份:2003
-
负责人:ISHIKAWA Makoto
-
依托单位:
Etiology of irritable bowel syndrome
-
批准号:63480198
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$3.65万
-
财政年份:1988
-
负责人:ISHIKAWA Makoto
-
依托单位:
国内基金
海外基金
TTP-Ago2相互作用调节miR16介导的ARE-mRNA降解
-
批准号:30670442
-
项目类别:面上项目
-
资助金额:25.0万元
-
批准年份:2006
-
负责人:周化民
-
依托单位: