A comprehensive study of the molecular mechanisms of associative learning by a behavioral genetic approach.
A comprehensive study of the molecular mechanisms of associative learning by a behavioral genetic approach.
批准号:
21370002
负责人:
IINO Yuichi
金额:
$12.48万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
The nematode C. elegans learns to avoid salt after the experience of starvation in the presence of salt. A pair of sensory neurons sense salt, but only the right member of this pair changes by learning through the effect of the C. elegans insulin. In addition, a protein known to be relevant to Alzheimer's desease was found closely related to the action of the insulin signal.
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Dopamine-dependent secretion of INS-1, an insulin-like peptide, regulates salt chemotaxis learning in C. elegans
INS-1(一种胰岛素样肽)的多巴胺依赖性分泌调节线虫的盐趋化性学习
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Lin CH, Tomioka M, Pereira S, Sellings L, Iino Y, van der Kooy D., Chia Hsun Anthony Lin, Takeshi Adachi, 富岡征大, 富岡征大, 富岡征大, Masahiro Tomioka, 富岡征大, 富岡征大, 富岡征大]
通讯作者:
富岡征大
Axonal transport of a new DAF-2 isoform governs associativelearning
新 DAF-2 同种型的轴突运输控制联想学习
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[新井佑佳, 内山洋司, 岡島敬一, 大野速雄]
通讯作者:
大野速雄
Sensing Salt : Plasticity in Sensory Systems and Behavioral Response
感觉盐:感觉系统的可塑性和行为反应
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Ohtsuka H, Azuma K, Murakami H, Aiba H., 飯野雄一]
通讯作者:
飯野雄一
DOI:
10.1523/jneurosci.4636-09.2010
发表时间:
2010-06-09
期刊:
JOURNAL OF NEUROSCIENCE
影响因子:
5.3
作者:
[Lin, Chia Hsun Anthony, Tomioka, Masahiro, van der Kooy, Derek]
通讯作者:
van der Kooy, Derek
DOI:
10.1093/nar/gkp868
发表时间:
2010-01
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Takayama J, Faumont S, Kunitomo H, Lockery SR, Iino Y]
通讯作者:
Iino Y
共 44 条
Study of the functions of the Ras-MAPK pathway and the insulin pathway in neural plasticity of C. elegans
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批准号:15370071
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.6万
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财政年份:2003
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负责人:IINO Yuichi
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依托单位:
Functional study of the Ras-MAP kinase pathway in the nervous system
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批准号:13480224
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.82万
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财政年份:2001
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负责人:IINO Yuichi
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依托单位:
Elucidation of The Molecular Mechanims of Chemotaxis and Its Plasticity in the Nematode Caenorhabditis elegans
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批准号:11680672
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.43万
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财政年份:1999
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负责人:IINO Yuichi
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依托单位:
Analysis of estrogen-induced genes in breast cancer
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批准号:06454359
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.1万
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财政年份:1995
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负责人:IINO Yuichi
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依托单位:
Systematic Search for the Genes that Program Sex Behavior in Caenorhabditis elegans
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批准号:07808093
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.34万
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财政年份:1995
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负责人:IINO Yuichi
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依托单位:
Identification of differential regulator of mitosis and meiosis
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批准号:03833006
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1991
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负责人:IINO Yuichi
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依托单位:
海外基金